Methodolgy | Advantages | Limitation |
---|---|---|
PET | Non-invasive, global and regional CFR measurable | Expensive, scarce, radiation exposure |
Intra-Coronary Doppler | CFR supplemented by measurement of fractional flow reserve provide stenosis-specific assessment | Invasive, expensive, radiation exposure |
TDE | Noninvasive, cheap especially without contrast agents, | Only regional flow velocity, mainly in the LAD is measured (lower feasibility of flow imaging in Cx and RCA), Difficult measurement of volumetric (absolute) coronary flow |