Table 2 TCD and cerebral blood flow modifications. MCA: middle cerebral artery. CPB: cardiopulmonary bypass. CBF: cerebral blood flow.
Author [reference] | Journal (Year of Publication) | Type of study and Number of patients | Main findings |
|---|---|---|---|
Lindegaard KF [4] | Stroke (1987) | Observational on 7 adult patients | Linear relationship between flow volume and blood velocity in MCA is present. |
Weyland A [5] | Anesthesiology (1994) | Observational on 15 adult patients | Linear relationship between flow volume and blood velocity in MCA is present before and after CPB but cannot reliably predict percentage changes in CBF during CPB. |
Bishop CCR [6] | Stroke (1986) | Observational on 17 adult patients | Changes in MCA velocity reliably correlate with changes with CBF evaluated with Xenon133 |
Rosemberg A [7] | Pediatric Research (1985) | Experimental in newborn lambs | Changes in cerebral blood flow velocity are useful qualitative measures of changes in cerebral blood flow |
Trivedi U [8] | Annals of Thoracic Surgery (1997) | Randomized trial on 60 adult patients receiving either α-stat or pH stat management based CPB | Measurement of MCA velocity by TCD expressed as relative changes of a pre-CPB level can be used to examine CBF changes during CPB |