Population | N | Age | Male | Diabetes | HTN | HLD | Smoking | CAD | EF | HS-SIC (SEM) | P-Value (vs control) |
---|---|---|---|---|---|---|---|---|---|---|---|
Healthy Controls | 20 | 34.7 ± 7.4 | 2 (10%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 65.7 ± 4.1 | 0.688 ± 0.074 | – |
Patient Cohorts | |||||||||||
Atypical Chest Pain or Palpitations | 127 | 37.3 ± 12.8 | 76 (60%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 62.5 ± 4.5 | 0.552 ± 0.049 | 0.016 |
Myocarditis | 44 | 40.0 ± 17.1 | 12 (27%) | 7 (15%) | 20 (45%) | 15 (34%) | 11 (25%) | 11 (25%) | 48.5 ± 16.5 | 0.425 ± 0.058 | 0.001 |
TTR Amyloidosis | 25 | 76.3 ± 9.7 | 6 (24%) | 6 (24%) | 17 (68%) | 19 (76%) | 9 (36%) | 6 (24%) | 46.6 ± 16.9 | 0.698 ± 0.103 | 0.85 |
STEMI | 20 | 59.1 ± 20.4 | 6 (30%) | 1 (5%) | 15 (75%) | 16 (80%) | 9 (45%) | 20 (100%) | 40.3 ± 12.9 | 0.881 ± 0.129 | 0.30 |
COVID | 39 | 67.6 ± 16.4 | 28 (72%) | 14 (36%) | 25 (64%) | 13 (33%) | 8 (21%) | 7 (18%) | 57.2 ± 10.8 | 0.904 ± 0.116 | 0.58 |
Severe Aortic Stenosis | 21 | 82.3 ± 9.7 | 8 (38%) | 5 (25%) | 18 (90%) | 16 (80%) | 8 (40%) | 14 (70%) | 60.7 ± 11.8 | 1.116 ± 0.196 | 0.38 |
Transplanted Cohorts | |||||||||||
No prior or active rejection | 5 | 49.6 ± 14.1 | 5 (100%) | 3 (60%) | 3 (60%) | 3 (60%) | 1 (20%) | 1 (20%) | 55.8 ± 1.9 | 1.191 ± 0.442 | 0.33 |
Prior but no active rejection | 15 | 54.9 ± 20.6 | 10 (67%) | 8 (53%) | 9 (60%) | 3 (20%) | 4 (27%) | 2 (13%) | 61.8 ± 3.8 | 0.594 ± 0.091 | 0.46 |
Active rejection | 22 | 48.5 ± 14.4 | 16 (73%) | 10 (45%) | 9 (41%) | 9 (41%) | 4 (18%) | 5 (23%) | 60.5 ± 6.8 | 0.478 ± 0.099 | 0.008 |
Total | 338 | 49.6 ± 20.9 | 169 (50%) | 54 (16%) | 116 (34%) | 94 (28%) | 54 (16%) | 66 (20%) | 57.4 ± 12.3 | 0.656 ± 0.032 | – |