Table 3 Univariable and multivariable cox regression analyses

Age, years

1.041

1.024–1.058

 < 0.001

1.036

1.014–1.058

0.001

Male

1.360

0.911–2.032

0.133

Creatinine, mg/dL

1.106

1.041–1.175

0.001

1.142

1.035–1.261

0.008

Hypertension

1.685

1.122–2.532

0.012

1.261

0.741–2.146

0.394

Diabetes mellitus

1.062

0.748–1.509

0.735

Atrial fibrillation

1.546

1.119–2.134

0.008

1.109

0.714–1.723

0.644

Ischemic etiology

1.104

0.792–1.538

0.558

NYHA III-IV vs. I-II

1.994

1.430–2.779

 < 0.001

1.094

0.714–1.676

0.680

Beta-blockers

0.623

0.365–1.063

0.083

ACEi/ARB

0.577

0.348–0.957

0.033

1.820

0.892–3.712

0.100

MRA

0.981

0.709–1.358

0.910

Diuretics

1.429

1.001–2.040

0.050

0.769

0.460–1.186

0.317

LVEDV, mL

1.004

1.001–1.006

0.002

1.003

0.999–1.006

0.115

LVEF, per % decrease

0.951

0.934–0.968

 < 0.001

1.029

1.001–1.059

0.046

LAVI, mL/m²

1.010

1.006–1.014

 < 0.001

0.999

0.992–1.007

0.827

PALS, per % decrease

1.080

1.055–1.107

 < 0.001

1.052

1.010–1.095

0.016

EROA, mm²

1.042

1.028–1.057

 < 0.001

1.031

1.007–1.056

0.012

SPAP, mmHg

1.031

1.020–1.042

 < 0.001

1.011

0.995–1.027

0.193

TAPSE, mm

0.931

0.896–0.967

 < 0.001

1.021

0.973–1.071

0.405

TR ≥ moderate

2.180

1.491–3.188

 < 0.001

0.887

0.556–1.415

0.614