Table 2 Correlations of functional and morphological properties of the arterial wall with clinical and laboratory parameters before PCSK9i treatment
Parameter | FMD | PWV | c-IMT |
|---|---|---|---|
Age (years) | r = -0.305; p = 0.002 | r = -0.247; p = 0.013 | r = -0.488; p < 0.0001 |
Body mass index (kg/m2) | r = -0.059; p = 0.56 | r = 0.104; p = 0.302 | r = 0.161; p = 0.112 |
Systolic blood pressure (mm Hg) | r = -0.094; p = 0.35 | r = -0.299; p = 0.003 | r = 0.207; p = 0.040 |
Diastolic blood pressure (mm Hg) | r = -0.047; p = 0.64 | r = 0.194; p = 0.053 | r = 0.008; p = 0.937 |
Total cholesterol (mmol/l) | r = -0.021; p = 0.837 | r = 0.076; p = 0.454 | r = -0.029; p = 0.776 |
HDL cholesterol (mmol/l) | r = 0.014; p = 0.892 | r = -0.009; p = 0.927 | r = 0.106; p = 0.296 |
LDL cholesterol (mmol/l) | r = 0.046; p = 0.652 | r = 0.081; p = 0.421 | r = -0.102; p = 0.314 |
Triglycerides (mmol/l) | r = -0.153; p = 0.129 | r = 0.018; p = 0.860 | r = 0.066; p = 0.517 |
Lipoprotein (a) (mg/l) | r = -0.231; p = 0.020 | r = 0.208; p = 0.038 | r = -0.067; p = 0.510 |
Apolipoprotein B (g/l) | r = 0.003; p = 0.977 | r = 0.062; p = 0.543 | r = -0.043; p = 0.677 |
Apolipoprotein A1 (g/l) | r = 0.030; p = 0.772 | r = -0.066; p = 0.517 | r = 0.150; p = 0.144 |
hs-CRP (mg/l) | r = -0.263; p = 0.009 | r = 0.079; p = 0.439 | r = -0.094; p = 0.358 |
TNF-alpha (ng/l) | r = 0.050; p = 0.625 | r = 0.171; p = 0.091 | r = -0.020; p = 0.843 |
Il-6 (ng/l) | r = -0.012; p = 0.907 | r = -0.055; p = 0.591 | r = -0.016; p = 0.876 |
IL-8 (ng/l) | r = 0.048; p = 0.636 | r = -0.035; p = 0.735 | r = -0.053; p = 0.605 |
IL-10 (ng/l) | r = 0.071; p = 0.486 | r = -0.078; p = 0.440 | r = 0-.025; p = 0.808 |
VCAM1 (mg/l) | r = -0.225; p = 0.025 | r = 0.042; p = 0.677 | r = 0.037; p = 0.715 |
TAFI (%) | r = -0.060; p = 0.561 | r = 0.109; p = 0.290 | r = 0.215; p = 0.036 |
PAI-1 (ng/ml) | r = 0.030; p = 0.129 | r = 0.218; p = 0.048 | r = 0.256; p = 0.020 |
OCP (Abs-sum) | r = -0.234 p = 0.021 | r = 0.057 p = 0.577 | r = 0.264 p = 0.009 |
OFP (%) | r = 0.119; p = 0.2 44 | r = -0.054; p = 0.602 | r = 0.004; p = 0.971 |
OHP (Abs-sum) | r = -0.264; p = 0.009 | r = 0.093; p = 0.367 | r = 0.144; p = 0.161 |