Table 3 Correlations of functional and morphological properties of the arterial wall with clinical and laboratory parameters after PCSK9i treatment
Parameter | FMD | PWV | c-IMT |
|---|---|---|---|
Age (years) | r = -0.3189; p = 0.061 | r = -0.334; p = 0.001 | r = -0.486; p < 0.0001 |
Body mass index (kg/m2) | r = -0.046; p = 0.435 | r = 0.096; p = 0.365 | r = 0.187; p = 0.142 |
Systolic blood pressure (mm Hg) | r = -0.286; p = 0.004 | r = 0.566; p < 0.0001 | r = 0.233; p = 0.021 |
Diastolic blood pressure (mm Hg) | r = -0.093; p = 0.361 | r = 0.386; p < 0.0001 | r = 0.097; p = 0.342 |
Total cholesterol (mmol/l) | r = -0.039; p = 0.701 | r = -0.044; p = 0.454 | r = -0.021; p = 0.834 |
HDL cholesterol (mmol/l) | r = 0.034; p = 0.738 | r = 0.001; p = 0.996 | r = 0.087; p = 0.339 |
LDL cholesterol (mmol/l) | r = 0-.036; p = 0.723 | r = -0.096; p = 0.342 | r = -0.01; p = 0.874 |
Triglycerides (mmol/l) | r = -0.071; p = 0.483 | r = 0.061; p = 0.546 | r = -0.013; p = 0.902 |
Lipoprotein (a) (mg/l) | r = 0.048; p = 0.638 | r = 0.061; p = 0.550 | r = -0.040; p = 0.697 |
Apolipoprotein B (g/l) | r = -0.060; p = 0.560 | r = -0.066; p = 0.522 | r = -0.039; p = 0.707 |
Apolipoprotein A1 (g/l) | r = 0.039; p = 0.705 | r = -0.014; p = 0.895 | r = 0.077; p = 0.454 |
hs-CRP (mg/l) | r = -0.107; p = 0.295 | r = 0.145; p = 0.153 | r = -0.038; p = 0.715 |
TNF-alpha (ng/l) | r = -0.035; p = 0.733 | r = 0.096; p = 0.350 | r = -0.029; p = 0.777 |
IL-6 (ng/l) | r = -0.124; p = 0.164 | r = 0.062; p = 0.548 | r = 0.109; p = 0.288 |
IL-8 (ng/l) | r = 0.131; p = 0.200 | r = 0.058; p = 0.527 | r = -0.015; p = 0.881 |
IL-10 (ng/l) | r = 0.026; p = 0.803 | r = -0.045; p = 0.664 | r = 0.152; p = 0.138 |
VCAM1 (mg/l) | r = -0.229; p = 0.024 | r = -0.060; p = 0.559 | r = -0.043; p = 0.677 |
TAFI (%) | r = 0.136; p = 0.194 | r = 0.148; p = 0.157 | r = -0.263; p = 0.011 |
PAI-1 (ng/ml) | r = -0.173; p = 0.122 | r = 0.055; p = 0.627 | r = 0.164; p = 0.146 |
OCP (Abs-sum) | r = -0.107 p = 0.296 | r = 0.147 p = 0.150 | r = 0.118 p = 0.251 |
OFP | r = -0.014 p = 0.893 | r = -0.122; p = 0.235 | r = -0.009; p = 0.929 |
OHP | r = -0.041; p = 0.687 | r = 0.172; p = 0.091 | r = 0.091; p = 0.378 |