Prevalence, one-year-incidence and predictors of carcinoid heart disease

Table 3 Right heart parameters at baseline and twelve-month follow-up of patients with carcinoid heart disease at baseline

	Patient 1		Patient 2		Patient 3
	Baseline	Follow-up	Baseline	Follow-up	Baseline	Follow-up
Duration from baseline to follow-up in months	10		11		11
NYHA class	I	II	III	III	IV	II
NTproBNP, ng/l	395	245	940	1799	1128	2727
Therapy
Cardiac intervention or operation (months since diagnosis)	None	Transcatheter pulmonary valve implantation (14)	None	Transcatheter pulmonary valve implantation (2)	None	Transcatheter pulmonary valve implantation (5)
Medication	ACE inhibitor, calcium antagonist, diuretics		ACE inhibitor, beta blocker, diuretics		ACE inhibitor, diuretics
LVEF, %	72	69	60	60	53	53
RVOT-VTI, cm	31	18	14	10	N. A	39
TAPSE, mm	26	32	18	14	19	22
RV-Sʹ, cm/s	14	16	15	14	17	16
MPEI	1.40	0.73	1.38	0.72	0.31	0.84
Free wall RV strain, %	-28.2	-38.3	-31.3	-25.9	N. A	N. A
Global RV strain, %	-33.5	-33.0	-26.6	-25.6	N. A	N. A
RVD basal, mm	39	51	40	41	42	46
RVD mid, mm	27	43	34	37	36	41
RV apex-base, mm	82	79	61	56	65	61
RVOT1, mm	35	35	38	35	39	39
RVOT2, mm	29	30	26	29	22	24
RA area, cm2	28	32	25	23	21	19
TR	severe	severe	severe	severe	severe	severe
TS	none	none	none	moderate	none	none
PR	severe	none^a	severe	mild^a	moderate	severe^a
PS	none	none^a	N. A	none^a	N. A	none^a

ACE inhibitor Angiotensin-converting-enzyme inhibitor, LVEF Left ventricular ejection fraction, MPEI Myocardial performance index, N. A, Not available, NTproBNP N-terminal-pro hormone B-type natriuretic peptide, NYHA New York Heart Association, PR Pulmonary regurgitation, PS Pulmonary stenosis, RA area Right atrium area, RV Right ventricular, RV apex-base Right ventricle apex to base, RVD Right ventricular diameter, RVOT Right ventricular outflow tract, RVOT-VTI Right ventricular outflow tract velocity time integral, RV-Sʹ Systolic tricuspid annular velocity, TAPSE Tricuspid annular plane systolic excursion, TR Tricuspid regurgitation, TS Tricuspid stenosis
^aEchocardiography was performed after patients had received transcatheter pulmonary valve implantation

ISSN: 1476-7120