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Table 1 Comparison of methods to measure CFR

From: Transthoracic Doppler echocardiography – noninvasive diagnostic window for coronary flow reserve assessment

Methodolgy

Advantages

Limitation

PET

Non-invasive, global and regional CFR measurable

Expensive, scarce, radiation exposure

Intra-Coronary Doppler

CFR supplemented by measurement of fractional flow reserve provide stenosis-specific assessment

Invasive, expensive, radiation exposure

TDE

Noninvasive, cheap especially without contrast agents,

Only regional flow velocity, mainly in the LAD is measured (lower feasibility of flow imaging in Cx and RCA), Difficult measurement of volumetric (absolute) coronary flow

  1. PET – positron emission tomography, TDE-transthoracic Doppler echocardiography