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Table 1 Comparison of methods to measure CFR

From: Transthoracic Doppler echocardiography – noninvasive diagnostic window for coronary flow reserve assessment

Methodolgy Advantages Limitation
PET Non-invasive, global and regional CFR measurable Expensive, scarce, radiation exposure
Intra-Coronary Doppler CFR supplemented by measurement of fractional flow reserve provide stenosis-specific assessment Invasive, expensive, radiation exposure
TDE Noninvasive, cheap especially without contrast agents, Only regional flow velocity, mainly in the LAD is measured (lower feasibility of flow imaging in Cx and RCA), Difficult measurement of volumetric (absolute) coronary flow
  1. PET – positron emission tomography, TDE-transthoracic Doppler echocardiography