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Table 3 Correlates of the E/A, e'/a' and E/e' ratios in stepwise regression by cohort

From: Prevalence of left ventricular diastolic dysfunction in European populations based on cross-validated diagnostic thresholds

Parameter Transmitral E/A Averaged TDI e'/a' E/e'
  FLEMENGHO EPOGH FLEMENGHO EPOGH FLEMENGHO EPOGH
R2 (%) 67.5 65.9 73.6 71.2 49.6 46.2
Adjusted R2 (%) 67.3 65.4 73.4 70.6 49.0 45.1
Partial regression coefficients     
Female (0,1)       
ß ± SE    0.064 ± 0.025* 0.084 ± 0.039* 0.62 ± 0.15‡ 0.37 ± 0.19*
Partial r2 (%)    0.22 0.29 1.4 0.44
Age
(+10 years)
      
ß ± SE -0.23 ± 0.008‡ -0.24 ± 0.012‡ -0.32 ± 0.009‡ -0.28 ± 0.015‡ 0.38 ± 0.048‡ 0.50 ± 0.068‡
Partial r2 (%) 53.6 51.4 61.1 54.4 33.6 35.4
BMI
(+1 kg/m2)
      
ß ± SE -0.017 ± 0.003‡ -0.011 ± 0.00‡ -0.031 ± 0.003‡ -0.026 ± 0.004‡ 0.093 ± 0.015‡ 0.078 ± 0.017‡
Partial r2 (%) 2.5 0.78 6.8 6.5 3.1 2.3
HR (+10 beats/minute)       
ß ± SE -0.13 ± 0.011‡ -0.13 ± 0.014‡ -0.11 ± 0.013‡ -0.13 ± 0.017‡ -0.16 ± 0.063†  
Partial r2 (%) 9.5 8.6 3.2 4.1 0.46  
SBP (+10 mmHg)       
ß ± SE 0.025 ± 0.008† 0.030 ± 0.012* 0.044 ± 0.010‡   0.36 ± 0.045‡ 0.36 ± 0.068‡
Partial r2 (%) 0.43 0.43 0.7   5.1 4.2
DBP (+10 mmHg)       
ß ± SE -0.075 ± 0.013‡ -0.079 ± 0.019‡ -0.12 ± 0.016‡ -0.071 ± 0.017‡ -0.21 ± 0.076† -0.27 ± 0.10†
Partial r2 (%) 0.97 1.5 1.7 1.7 0.70 0.82
LVMI (+10 g/m2)       
ß ± SE     -0.025 ± 0.011* 0.16 ± 0.032‡ 0.13 ± 0.049†
Partial r2 (%)     0.67 1.4 0.49
LV length (+1 cm)       
ß ± SE      -0.53 ± 0.10‡ -0.45 ± 0.13‡
Partial r2 (%)      3.8 1.8
  1. Values are mutually adjusted partial regression coefficients ± SE. BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVMI, left ventricle mass index. Significance of the partial regression coefficient: * P < 0.05, †P < 0.01, and ‡P < 0.001. There were no differences between the partial regression coefficients in two studies (P ≥ 0.10)