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Table 3 Correlates of the E/A, e'/a' and E/e' ratios in stepwise regression by cohort

From: Prevalence of left ventricular diastolic dysfunction in European populations based on cross-validated diagnostic thresholds

Parameter

Transmitral E/A

Averaged TDI e'/a'

E/e'

 

FLEMENGHO

EPOGH

FLEMENGHO

EPOGH

FLEMENGHO

EPOGH

R2 (%)

67.5

65.9

73.6

71.2

49.6

46.2

Adjusted R2 (%)

67.3

65.4

73.4

70.6

49.0

45.1

Partial regression coefficients

    

Female (0,1)

      

ß ± SE

  

0.064 ± 0.025*

0.084 ± 0.039*

0.62 ± 0.15‡

0.37 ± 0.19*

Partial r2 (%)

  

0.22

0.29

1.4

0.44

Age

(+10 years)

      

ß ± SE

-0.23 ± 0.008‡

-0.24 ± 0.012‡

-0.32 ± 0.009‡

-0.28 ± 0.015‡

0.38 ± 0.048‡

0.50 ± 0.068‡

Partial r2 (%)

53.6

51.4

61.1

54.4

33.6

35.4

BMI

(+1 kg/m2)

      

ß ± SE

-0.017 ± 0.003‡

-0.011 ± 0.00‡

-0.031 ± 0.003‡

-0.026 ± 0.004‡

0.093 ± 0.015‡

0.078 ± 0.017‡

Partial r2 (%)

2.5

0.78

6.8

6.5

3.1

2.3

HR (+10 beats/minute)

      

ß ± SE

-0.13 ± 0.011‡

-0.13 ± 0.014‡

-0.11 ± 0.013‡

-0.13 ± 0.017‡

-0.16 ± 0.063†

 

Partial r2 (%)

9.5

8.6

3.2

4.1

0.46

 

SBP (+10 mmHg)

      

ß ± SE

0.025 ± 0.008†

0.030 ± 0.012*

0.044 ± 0.010‡

 

0.36 ± 0.045‡

0.36 ± 0.068‡

Partial r2 (%)

0.43

0.43

0.7

 

5.1

4.2

DBP (+10 mmHg)

      

ß ± SE

-0.075 ± 0.013‡

-0.079 ± 0.019‡

-0.12 ± 0.016‡

-0.071 ± 0.017‡

-0.21 ± 0.076†

-0.27 ± 0.10†

Partial r2 (%)

0.97

1.5

1.7

1.7

0.70

0.82

LVMI (+10 g/m2)

      

ß ± SE

   

-0.025 ± 0.011*

0.16 ± 0.032‡

0.13 ± 0.049†

Partial r2 (%)

   

0.67

1.4

0.49

LV length (+1 cm)

      

ß ± SE

    

-0.53 ± 0.10‡

-0.45 ± 0.13‡

Partial r2 (%)

    

3.8

1.8

  1. Values are mutually adjusted partial regression coefficients ± SE. BMI, body mass index; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVMI, left ventricle mass index. Significance of the partial regression coefficient: * P < 0.05, †P < 0.01, and ‡P < 0.001. There were no differences between the partial regression coefficients in two studies (P ≥ 0.10)