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Table 3 Indications to PFO Closure

From: Percutaneous treatment of patients with heart diseases: selection, guidance and follow-up. A review

CLINICAL INDICATIONS

CLINICAL CONTRAINDICATIONS

ECHOCARDIOGRAPHIC INDICATIONS

ECHOCARDIOGRAPHIC CONTRAINDICATIONS

Cryptogenic Strokes

Migraine with Aura

+

Thrombophylia

and/or

Peripheral Venous Thrombosis

and/or

Previous History of Paradoxical Embolism

Severe Pulmonary Hypertension

Recent Gastrointestinal Bleeding

Controndications to Antiplatelet or Anticoagulant Therapy

Infection at the Time of Implantation

Atrial Septal Aneurysm

and/or

Large Size of PFO (≥ 4 mm)

and/or

Long Tunnel of PFO (≥ 1 cm)

and/or

Severe Right to Left Shunting (> 30 Bubles)

and/or

Shunting at Rest

Other Congenital Heart Defects

Eustachian valve and ChiariNetwork