LV twist changes for the first and last beat in a sequence of eight consecutive beats in a vena cava occlusion manoeuvre were analysed by speckle tracking imaging. Left ventricular twist increased significantly in control group and in positive inotropic condition. There was a trend to increase but no significance was reached in negative inotropic condition. Both individual and grouped values are presented. CTRL = control group, ADR = adrenaline group, BB = beta-blockade group. # = p < 0.05 using Wilcoxons Signed Rank test vs. first beat.