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Table 2 Left ventricular parameters during control, adrenaline and beta-blockade

From: Left ventricular twist is load-dependent as shown in a large animal model with controlled cardiac load

  

Control

Adrenaline

 

Beta blockade

 

Apnea measurement

HR

(bpm)

125 ± 19

147 ± 29

 

101 ± 12

 

SV

(mL)

60 ± 9

65 ± 26

 

50 ± 17

#

CO

(L/min)

7.4 ± 1.3

9.3 ± 3.8

 

5.0 ± 1.7

#

Ves

(mL)

40.9 ± 4.4

37.8 ± 15.3

 

55.8 ± 10.4

#

Ved

(mL)

96.5 ± 8.4

100.3 ± 31.9

 

101.6 ± 22.6

 

Pes

(mm Hg)

119.0 ± 7.4

121.8 ± 5.1

 

106.7 ± 16.0

 

Ped

(mm Hg)

15.6 ± 5.2

15.8 ± 6.7

 

19.6 ± 5.7

 

dPdt max

(mm Hg/s)

2830 ± 430

5483 ± 14

#

1726 ± 594

#

EF

(%)

62.0 ± 6.1

64.9 ± 14.0

 

47.7 ± 8.0

#

SW

(mm Hg mL)

6744 ± 1054

8254 ± 3061

 

4608 ± 1858

#

dPdt min

(mm Hg/s)

−2889 ± 193

−3483 ± 680

 

−2051 ± 553

 

Tau

(ms)

33.9 ± 4.8

24.5 ± 2.2

#

48.6 ± 25.9

 

PHT

(ms)

20.8 ± 2.4

15.6 ± 2.1

#

32.0 ± 14.6

#

PWRmax

(mm Hg mL/s)

50210 ± 9173

72286 ± 30668

 

35756 ± 10130

#

PWRmax/EDV2

 

5.46 ± 1.15

8.30 ± 4.24

 

3.62 ± 0.94

#

dPdt/EDV

(mm Hg/s/mL)

29.7 ± 5.8

63.1 ± 29.5

#

18.0 ± 9.8

#

VCBO measurement

Ees

(mm Hg/mL)

0.95 ± 0.32

1.65 ± 1.00

#

1.03 ± 0.61

 

PRSW

(mm Hg)

83.4 ± 12.5

100.1 ± 28.5

 

56.6 ± 18.3

#

  1. HR = heart rate; SV = stroke volume; CO = cardiac output; Ves = end-systolic volume; Ved = end-diastolic volume; Pes = end-systolic pressure; Ped = end-diastolic pressure; dPdt max = maximal rate of pressure increase; EF = ejection fraction; SW = stroke work; Tau = isovolumic relaxation time constant; PHT = pressure half time during diastole: dPdt min = maximal rate of pressure decrease; PWRmax = maximal power; Ees = end-systolic elastance; PRSW = preload recruitable stroke work. Data are presented as mean ± 95% confidence intervals, n = 7. # = p < 0.05 using Wilcoxons Signed Rank test vs. Control.