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Table 3 Single parameters selected as significant predictors of coronary stenosis in separate myocardial segments

From: Quantitative approach using multiple single parameters versus visual assessment in dobutamine stress echocardiography

Method

Parameter

Cut-off

AUC (95 % CI)

Sensitivity % (95 % CI)

Specificity % (95 % CI)

Accuracy % (95 % CI)

Youden index

Basal inferoseptal segment

PW-DMI

T to S' stress

70.5

0.66* (0.54;0.78)

56.7 (37.4;74.5)

76.7 (68.1;83.9)

72.7 (64.8;79.6)

0.33

 

S' stress - S' rest

4.15

0.65* (0.53;0.76)

56.7 (37.4;74.5)

73.1 (64.2;80.8)

69.8 (61.7;77.0)

0.30

 

A' stress

12.3

0.64* (0.53;0.75)

46.7 (28.3;65.7)

81.4 (73.0;88.1)

74.1 (66.1;81.1)

0.28

CC-DMI

E'/A' rest

0.64

0.66* (0.55;0.76)

64.3 (44.1;81.4)

68.2 (58.6;76.7)

67.4 (58.9;75.1)

0.33

STI

E' stress

4.5

0.70* (0.58;0.83)

66.7 (44.7;84.4)

71.6 (61.0;80.7)

70.5 (61.2;78.8)

0.38

 

E'/A' stress

0.34

0.66* (0.52;0.80)

47.6 (25.7;70.2)

88.1 (79.2;94.1)

80.0 (71.1;87.2)

0.36

Mid inferoseptal segment

CC-DMI

PSI stress /SS stress

0.13

0.65* (0.54;0.77)

58.1 (39.1;75.5)

69.1 (59.6;77.6)

66.7 (58.2;74.4)

0.27

 

SSR stress - SSR rest

−0.21

0.64* (0.53;0.74)

74.2 (55.4;88.1)

55.9 (46.1;65.3)

59.9 (51.3;68.0)

0.30

Apical inferoseptal segment

STI

PSI rest /SS rest

−0.15

0.65*(0.54;0.76)

70.0 (50.6;85.3)

57.9 (48.3;67.1)

60.4 (51.9;68.5)

0.28

 

PSI rest

3.85

0.65*(0.54;0.76)

70.0 (50.6;85.3)

56.1 (46.5;65.4)

59.0 (50.5;67.1)

0.26

 

RSSR rest

1.95

0.63*(0.53;0.74)

90.0 (73.5;97.9)

34.2 (25.6;43.7)

45.8 (37.5;54.3)

0.24

Basal inferior segment

PW-DMI

S' stress

10.8

0.65* (0.53;0.76)

48.3 (29.4;67.5)

77.3 (68.7;84.5)

71.6 (63.6;78.7)

0.26

 

S' stress - S' rest

4.8

0.64* (0.53;0.75)

75.9 (56.5;89.7)

52.1 (42.8;61.3)

56.8 (48.4;64.9)

0.28

 

T to S' stress - T to S' rest

−45.5

0.64* (0.53;0.75)

62.1 (42.3;79.3)

65.5 (56.3;74.0)

64.9 (56.6;72.5)

0.28

 

(T to S' stress - T to S' rest )/T to S' rest

−0.44

0.66* (0.55;0.76)

69.0 (49.2;84.7)

58.0 (48.6;67.0)

60.1 (51.8;68.1)

0.27

 

E' rest

9.35

0.64* (0.54;0.74)

93.3 (77.9;99.2)

34.2 (25.8;43.4)

46.0 (37.8;54.3)

0.28

 

E' stress

7.53

0.72* (0.62;0.82)

72.4 (52.8;87.3)

66.1 (56.7;74.7)

67.4 (59.1;74.9)

0.39

CC-DMI

PSI stress /PSS stress

0.06

0.65* (0.52;0.78)

66.7 (44.7;84.4)

61.9 (51.4;71.5)

62.8 (53.6;71.4)

0.29

STI

SS rest

−13.0

0.65* (0.54;0.77)

41.4 (23.5;61.1)

88.7 (81.4;93.8)

79.2 (71.6;85.5)

0.30

Mid inferior segment

PW-DMI

T to S' stress - T to S' rest

−41.9

0.64* (0.53;0.75)

66.7 (47.2;82.7)

64.1 (54.7;72.8)

64.6 (56.3;72.3)

0.31

CC-DMI

SS stress

−14.5

0.66* (0.56;0.76)

75.0 (55.1;89.3)

55.8 (46.1;65.1)

59.6 (51.0;67.7)

0.31

STI

PSSR rest

−0.65

0.64* (0.52;0.76)

41.4 (23.5;61.1)

87.0 (79.4;92.5)

77.8 (70.1;84.3)

0.28

 

(PSI stress - PSI rest )/PSI rest

−0.08

0.67* (0.56;0.78)

48.3 (29.4;67.5)

81.3 (72.8;88.0)

74.5 (66.4;81.4)

0.30

Basal anterior segment

PW-DMI

S' stress

8.2

0.63* (0.52;0.74)

75.8 (57.7;88.9)

44.2 (34.9;53.9)

51.4 (43.0;59.7)

0.20

CC-DMI

S' stress

6.2

0.69* (0.59;0.79)

51.7 (32.5;70.6)

81.3 (72.8;88.0)

75.2 (67.2;82.1)

0.33

 

(PS' stress - PS' rest )/PS' rest

3.1

0.69* (0.54;0.84)

53.3 (26.6;78.7)

83.1 (71.0;91.6)

77.0 (65.8;86.0)

0.36

 

SSR stress

−2.4

0.65* (0.54;0.75)

80.0 (61.4;92.3)

52.7 (43.0;62.2)

58.5 (49.9;66.7)

0.33

STI

PSI stress - PSI rest

−5.5

0.64* (0.53;0.75)

40.0 (22.7;59.4)

87.3 (79.6;92.9)

77.1 (69.3;83.8)

0.27

 

PSSR rest

−1.1

0.68* (0.58;0.78)

80.0 (61.4;92.3)

47.4 (37.9;56.9)

54.2 (45.7;62.5)

0.27

 

PSSR stress - PSSR rest

−0.39

0.67* (0.56;0.78)

80.0 (61.4;92.3)

56.8 (47.0;66.1)

61.7 (53.1;69.8)

0.37

Basal inferolateral segment

PW-DMI

S' stress

12.1

0.65* (0.54;0.76)

70.4 (49.8;86.2)

57.3 (47.8;66.4)

59.7 (51.2;67.8)

0.28

 

E' stress

8.1

0.66* (0.53;0.78)

64.0 (42.5;82.0)

68.7 (59.4;77.0)

67.9 (59.4;75.5)

0.33

 

E'/A' stress

0.51

0.69* (0.57;0.80)

56.0 (34.9;75.6)

76.3 (67.4;83.8)

72.7 (64.5;79.9)

0.32

Mid inferolateral segment

CC-DMI

E'/A' rest

0.5

0.65* (0.54;0.76)

61.5 (40.6;79.8)

70.9 (61.5;79.2)

69.1 (60.6;76.8)

0.32

 

SS stress

−16.0

0.72* (0.62;0.82)

80.8 (60.6;93.4)

59.8 (50.1;69.0)

63.8 (55.2;71.8)

0.41

 

SSR stress

−1.4

0.68* (0.56;0.80)

64.0 (42.5;82.0)

71.2 (61.8;79.4)

69.9 (61.4;77.4)

0.35

Mid anteroseptal segment

PW-DMI

PS' stress - PS' rest

1.8

0.66* (0.55;0.76)

86.2 (68.3;96.1)

52.3 (42.5;62.1)

59.6 (50.8;67.9)

0.39

 

(PS' stress - PS' rest )/PS' rest

0.86

0.70* (0.58;0.82)

81.8 (59.7;94.8)

70.2 (59.3;79.7)

72.6 (63.1;80.9)

0.52

CC-DMI

E' stress

3.5

0.72* (0.61;0.83)

84.6 (65.1;95.6)

51.2 (39.9;62.4)

59.3 (49.4;68.6)

0.36

STI

PSI stress /SS stress

0.14

0.64* (0.54;0.75)

67.9 (47.6;84.1)

59.0 (49.0;68.5)

60.9 (52.1;69.2)

0.27

  1. P ≤ 0.025 for AUC > 0.5, * P < 0.05 compared with AUC of visual assessment 0.88; PW-DMI = pulsed wave Doppler myocardial imaging; CC-DMI = color coded Doppler myocardial imaging; STI = speckle tracking imaging; AUC = area under the curve; CI = confidence interval; S' = peak systolic velocity; PS' = peak post-systoloc velocity; E' = early diastolic wave; A' = late diastolic wave; SS = peak systolic strain, PSS = peak post-systolic strain; PSI = post-systolic index; SSR = systolic strain rate; PSSR = post-systolic strain rate; T = time; RSSR = radial systolic strain rate; RPSSR = radial post-systolic strain rate.