| |
ARVC (n = 17)
|
Relatives (n = 19)
|
Controls (n = 22)
|
P-value*
|
|---|
|
Mean (SD)
|
Mean (SD)
|
Mean (SD)
|
|---|
|
LV diameter (mm)
|
52.6 (6.4)
|
54.6 (4.4)
|
51.3 (2.9)
|
0.009
|
|
RVOT/BSA (cm/m
2
)
|
2.0 (0.4)
|
1.6 (0.2)
|
1.6 (0.2)
|
0.981
|
|
RVIT/BSA (cm/m
2
)
|
2.3 (0.5)
|
1.9 (0.2)
|
1.8 (0.2)
|
0.674
|
|
LVOT VTI (cm)
|
18.8 (5.5)
|
21.3 (2.5)
|
20.9 (2.4)
|
0.555
|
|
TAPSE (mm)
|
19.1 (5.0)
|
25.3 (2.9)
|
25.3 (3.0)
|
0.963
|
|
Sw lat. LV (cm/s)
|
6.6 (2.3)
|
7.3 (1.2)
|
8.5 (1.9)
|
0.018
|
|
Sw Sept. (cm/s)
|
5.7 (1.6)
|
6.6 (1.0)
|
7.1 (0.9)
|
0.115
|
|
Sw RV free wall (cm/s)
|
8.2 (2.5)
|
11.2 (1.9)
|
11.6 (1.7)
|
0.545
|
|
E/A LV
|
1.3 (0.5)
|
1.8 (0.6)
|
1.7 (0.4)
|
0.600
|
|
E/E’ LV
|
8.8 (3.2)
|
6.4 (2.1)
|
6.1 (1.6)
|
0.608
|
|
2D strain LV base (%)
|
−17.3 (4.4)
|
−19.6 (2.7)
|
−20.2 (3.5)
|
0.518
|
|
2D strain LV mid (%)
|
−15.3 (4.9)
|
−18.3 (3.2)
|
−18.3 (2.4)
|
0.968
|
|
2D strain sept base (%)
|
−14.9 (3.6)
|
−15.8 (2.9)
|
−17.8 (2.5)
|
0.025
|
|
2D strain sept mid (%)
|
−15.2 (5.6)
|
−18.5 (2.9)
|
−18.2 (2.1)
|
0.636
|
|
2D strain RV base (%)
|
−16.0 (6.8)
|
−26.8 (2.9)
|
−28.5 (3.6)
|
0.121
|
|
2D strain RV mid (%)
|
−18.9 (5.9)
|
−27.3 (4.5)
|
−27.2 (3.5)
|
0.945
|
- * Controls vs. relatives using Student’s t-test.
- Right ventricular outflow and inflow diameter related to BSA(RVOT/BSA resp.RVIT/BSA), Left ventricular outflow velocity time integral (LVOT VTI), tricuspid annular plane systolic excursion (TAPSE), systolic velocity at AV-plane in lateral LV (SwLV), septum (Sw sept) and RV wall (Sw RV).
