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Table 4 Impact of high global left ventricular load on patient outcome in multivariate Cox regression analyses

From: Global left ventricular load in asymptomatic aortic stenosis: covariates and prognostic implication (the SEAS trial)

 

Primary model

 

Secondary model §

 

HR (95% CI) ‡

P

HR (95% CI) §

P

Major CV events

1.49 (1.19-1.86)

<0.001

1.35 (1.08-1.69)

0.010

Aortic valve events

1.55 (1.23-1.95)

<0.001

1.41(1.12-1.78)

0.004

Ischemic CV events

0.99 (0.71-1.39)

0.962

0.91 (0.65-1.28)

0.589

Total Mortality

1.36 (0.91-2.02)

0.138

1.29 (0.86-1.95)

0.215

  1. CV: cardiovascular.
  2. ‡Primary model included: Zva, randomized study treatment, hypertension, LV ejection fraction, female gender, age and abnormal LV geometry.
  3. § Secondary model included: all covariates in the primary model as well as peak aortic jet velocity and mean aortic gradient.