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Table 1 Echocardiographic measurements from B-mode images

From: Transthoracic echocardiography reference values in juvenile and adult 129/Sv mice

Measurement

Juvenile

n

Adult

n

p

LVEndoLd (mm)

6.18 (0.57)

15

7.40 (0.58)

15

< 0.001

LVEndoLs (mm)

4.99 ± 0.38

15

6.58 ± 0.45

15

< 0.001

LVEpiLd (mm)

6.38 (0.56)

15

7.65 (0.67)

15

< 0.001

LVEpiLs (mm)

5.35 ± 0.34

15

7.03 ± 0.44

15

< 0.001

LVEndoAd (mm2)

6.06 ± 0.87

15

9.87 ± 1.20

15

< 0.001

LVEndoAs (mm2)

3.06 (0.98)

15

4.25 (1.12)

15

< 0.001

LVEpiAd (mm2)

11.85 ± 1.73

15

19.47 ± 1.71

15

< 0.001

LVEpiAs (mm2)

8.84 ± 1.83

15

14.46 ± 1.57

15

< 0.001

EAC (mm2)

3.22 ± 0.81

15

5.62 ± 1.16

15

< 0.001

FAC (%)

52.89 ± 10.07

15

56.87 ± 7.80

15

ns

LVVd (μl)

29.57 ± 6.04

15

59.90 ± 8.78

15

< 0.001

LVVs (μl)

11.85 ± 3.19

15

23.32 ± 5.31

15

< 0.001

LVM (mg)

39.68 ± 8.64

15

81.90 ± 9.69

15

< 0.001

LVMi (mg/g)

5.26 ± 1.27

15

4.16 ± 0.42

15

0.005

AoD (mm)

0.93 ± 0.09

15

1.27 ± 0.13

15

< 0.001

PAD (mm)

1.34 ± 0.11

15

1.59 ± 0.13

15

< 0.001

  1. Values are mean ± SD or median (IQR), as appropriate. p = statistical significance; ns = not significant. n = 15 for all measurements.
  2. LVEndoL = Left ventricle endocardial length. LVEpiL = Left ventricle epicardial length. LVEndoA = Left ventricle endocardial area. LVEpiA = Left ventricle epicardial area. EAC = Endocardial area change. FAC = Fractional area change. LVV = Left ventricle volume. LVM = Left ventricle mass. LVMi = LVM index. AoD = Ascending aorta diameter. PAD = Pulmonary artery diameter. -d = In diastole. -s = In systole.