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Table 3 Echocardiographic measurements from Doppler images

From: Transthoracic echocardiography reference values in juvenile and adult 129/Sv mice

Measurement Juvenile n Adult n p
AoVPV (mm/s) 1055.28 (327.21) 15 1557.67 (693.61) 15 0.003
AET (ms) 50.37 ± 4.56 15 49.59 ± 4.50 15 ns
AoVPPG (mmHg) 4.45 (3.13) 15 9.76 (9.46) 15 0.003
DAoPV (mm/s) 747.59 (162.89) 15 1049.88 (321.15) 15 0.002
SV (μl) 31.93 ± 8.67 15 70.61 ± 24.66 15 < 0.001
CO (ml/min) 12.06 ± 4.05 15 29.71 ± 10.13 15 < 0.001
COi (ml/min.g) 1.54 ± 0.36 15 1.48 ± 0.39 15 ns
PVPV (mm/s) 663.34 ± 141.08 15 810.62 ± 149.55 15 0.01
PVPPG (mmHg) 1.83 ± 0.77 15 2.71 ± 0.96 15 0.01
MVE (mm/s) 673.53 ± 149.31 15 747.08 ± 92.31 15 ns
MVA (mm/s) 456.51 ± 73.29 15 500.17 ± 85.14 15 ns
IVCT (ms) 10.90 ± 2.76 15 12.91 ± 3.45 15 ns
IVRT (ms) 16.52 ± 3.29 15 12.48 ± 2.49 15 0.001
MVET (ms) 61.05 ± 9.74 15 59.24 ± 8.34 15 ns
NFT (ms) 77.45 ± 5.66 15 75.66 ± 7.57 15 ns
MVPPG (mmHg) 1.98 ± 0.76 15 2.30 ± 0.52 15 ns
MVE/A 1.50 ± 0.37 15 1.53 ± 0.27 15 ns
LVMPI 0.55 ± 0.14 15 0.51 ± 0.07 15 ns
TVE (mm/s) 241.72 ± 30.57 12 252.83 ± 77.42 6 ns
TVA (mm/s) 400.90 ± 47.96 12 386.53 ± 123.06 6 ns
TVPPG (mmHg) 0.74 ± 0.21 12 0.68 ± 0.39 6 ns
TVE/A 0.60 ± 0.06 12 0.66 ± 0.13 6 ns
  1. Values are mean ± SD or median (IQR), as appropriate. p = statistical significance. ns = not significant. n = 15 for all measurements, except for TV measurements (n = 12 for the juveniles and n = 6 for the adults).
  2. AoVPV = Ascending aorta valve peak velocity. AET = Aortic ejection time. AoVPPG = Ascending aorta valve peak pressure gradient. DAoPV = Descending aorta peak velocity. SV = Stroke volume. CO = Cardiac output. COi = CO index. PVPV = Pulmonary valve peak velocity. PVPPG = Pulmonary valve peak pressure gradient. MVE = Mitral valve early wave peak. MVA = Mitral valve atrial wave peak. IVCT = Isovolumic contraction time. IVRT = Isovolumic relaxation time. MVET = Mitral valve ejection time. NFT = No Flow Time. MVPPG = Mitral valve peak pressure gradient. LVMPI = Left ventricle myocardial performance index. TVE = Tricuspid valve early wave peak. TVA = Tricuspid valve atrial wave peak. TVPPG = Tricuspid valve peak pressure gradient.