Bilateral common carotid artery ultrasound for prediction of incident strokes using intima-media thickness and external diameter: an observational study

Eigenbrodt, Marsha L; Evans, Gregory W; Rose, Kathryn M; Bursac, Zoran; Tracy, Richard E; Mehta, Jawahar L; Couper, David J

doi:10.1186/1476-7120-11-22

Table 3 Gender-specific percentages and means of baseline characteristics for right and left common carotid artery geometries

From: Bilateral common carotid artery ultrasound for prediction of incident strokes using intima-media thickness and external diameter: an observational study

	Mean±SD or n (%) for				Mean±SD or n (%) for
	RCCA Geometries defined by large* component(s):				LCCA Geometries defined by large* component(s):
	IMT +	IMT	Diameter	Neither	IMT +	IMT	Diameter	Neither
	Diameter	Only	Only		Diameter	Only	Only
Women	N=1307	N=751	N=755	N=1294	N=1391	N=795	N=668	N=1253
Age, y	55.9±5.5^†	53.9±5.5^†	53.5±5.6^†	51.4±5.2	55.9±5.6^†	53.8±5.6^†	53.3±5.5^†	51.5±5.2
Race, black	507 (38.8)^†	226 (30.1)^†	224 (29.7)^†	262 (20.2)	507 (36.4)^†	197 (24.8)	246 (36.8)^†	269 (21.5)
CHD	43 (3.3)^†	13 (1.7)^§	8 (1.1)	7 (0.5)	41 (2.9)^†	11 (1.4)	11 (1.6)^§	8 (0.6)
Carotid lesions	554 (46.9)^†	227 (34.6)^†	193 (27.8)^§	279 (23.7)	548 (44.0)^†	241 (33.8)^†	178 (29.1)	286 (25.1)
Hypertension	634 (48.5)^†	199 (26.5)^†	252 (33.4)^†	236 (18.2)	659 (47.4)^†	207 (26.0)^†	229 (34.3)^†	226 (18.0)
Diabetes mellitus	202 (15.5)^†	64 (8.5)^†	50 (6.6)^§	58 (4.5)	194 (13.9)^†	67 (8.4)^†	56 (8.4)^‡	57 (4.5)
Current smoker	357 (27.3)	164 (21.8)	230 (30.5)^‡	319 (24.7)	391 (28.1)^§	194 (24.4)	191 (28.6)^§	294 (23.5)
Current drink	596 (45.6)^†	394 (52.5)^†	381 (50.5)^†	794 (61.4)	654 (47.0)^†	436 (54.8)	334 (50.0)^†	741 (59.1)
Systolic BP mm Hg	128±22^†	116±16^†	121±19^†	112±16	128±22^†	116±15^†	121±19^†	113±16
Diastolic BP mm Hg	73±12^†	71±10^§	72±11^†	70±10	73±12^†	71±10^§	73±11^†	70±10
Height, cm	163.0±5.9^‡	162.0±6.0	163±6.0^§	162.3±5.7	162.9±6.0^‡	161.9±5.8	163.1±5.9^‡	162.3±5.8
BMI, kg/m²	28.0±5.7^†	26.5±5.0^†	27.3±5.8^†	25.5±4.7	27.8±5.6^†	26.5±5.1^†	27.5±5.9^†	25.5±4.7
Glucose, IU	6.32±2.94^†	5.76±1.92^‡	5.69±1.65^§	5.51±1.27	6.21±2.76^†	5.80±1.90^†	5.80±2.05^†	5.49±1.28
HDL, IU	1.46±0.43^†	1.55±0.45	1.50±0.47^‡	1.57±0.45	1.45±0.44^†	1.54±0.45	1.54±0.47	1.57±0.43
LDL, IU	3.65±1.05^†	3.56±1.05^†	3.41±1.06^‡	3.27±1.03	3.65±1.06^†	3.54±1.04^†	3.39±1.10^§	3.27±0.99
Fibrinogen, mg/dL	314±71^†	298±56	308±64^†	293±57	315±69^†	299±61^§	303±62^†	293±57
WBC, 1000s/mm³	6.00±1.86	5.72±1.76	6.01±1.92	5.86±1.79	6.00±1.88^‡	5.94±1.81	5.89±1.87	5.80±1.77
Triglyceride, IU	1.35±0.67^†	1.28±0.65^†	1.27±0.63^‡	1.18±0.60	1.35±0.67^†	1.29±0.64^†	1.24±0.64^§	1.18±0.59
Prevalent stroke	37 (2.8)	11 (1.5)	20 (2.6)	25 (1.9)	32 (2.3)	10 (1.3)	28 (4.2)^‡	23 (1.8)
MEN	N=1068	N=599	N=598	N=1065	N=1074	N=607	N=599	N=1050
Age, y	56.5±5.5^†	55.1±5.6^†	53.7±5.8^†	52.4±5.4	56.4±5.5^†	54.6±5.6^†	53.9±5.7^†	52.6±5.5
Race, black	311 (29.1)^†	171 (28.5)^†	131 (21.9)	218 (20.5)	294 (27.4)^‡	147 (24.2)	160 (26.7)^§	230 (21.9)
CHD	100 (9.4)^†	59 (9.8)^†	38 (6.4)	56 (5.3)	111 (10.3)^†	58 (9.6)^†	36 (6.0)	48 (4.6)
Carotid lesions	551 (58.7)^†	264 (50.8)^†	231 (43.3)^†	324 (34.1)	546 (57.9)^†	275 (52.0)^†	216 (40.5)	333 (35.5)
Hypertension	466 (43.6)^†	174 (29.0)^‡	214 (35.8)^†	235 (22.1)	470 (43.8)^†	184 (30.3)^†	208 (34.7)^†	227 (21.6)
Diabetes mellitus	153 (14.3)^†	76 (12.7)^†	56 (9.4)^§	67 (6.3)	152 (14.2)^†	75 (12.4)^†	61 (10.2)^‡	64 (6.1)
Current smoker	344 (32.2)^†	156 (26.0)	207 (34.6)^†	263 (24.7)	361 (33.6)^†	157 (25.9)	187 (31.2)^§	265 (25.2)
Current drink	667 (62.5)	389 (64.9)	408 (68.2)	705 (66.2)	672 (62.6)^§	395 (65.1)	398 (66.4)	704 (67.0)
Systolic BP, mm Hg	129±20^†	119±16^‡	123±19^†	116±14	128±21^†	120±16^†	124±19^†	116±14
Diastolic BP, mmHg	77±13^†	74±11	76±12^§	74±10	76±13^†	75±11	76±12^†	74±10
Height, cm	176.6±6.4^§	175.7±6.5	177.5±6.4^†	176.0±6.3	176.6±6.4^‡	175.5±6.3	177.7±6.4^†	175.8±6.4
BMI, kg/m²	27.6±4.1^†	26.7±3.8^§	26.9±3.9^‡	26.3±3.5	27.5±4.0^†	26.8±3.7^§	27.0±3.9^†	26.4±3.6
Glucose, IU	6.28±2.39^†	6.21±2.34^†	5.92±1.66^§	5.74±1.09	6.25±2.34^†	6.16±2.20^†	5.98±1.77^§	5.75±1.23
HDL, IU	1.17±0.37	1.16±0.34	1.21±0.43^§	1.16±0.34	1.17±0.37	1.13±0.32^‡	1.22±0.45^§	1.17±0.34
LDL, IU	3.65±0.95^§	3.71±0.97^†	3.48±0.96	3.54±0.94	3.65±0.98^‡	3.70±0.95^†	3.52±0.96	3.53±0.92
Fibrinogen, mg/dL	305±67^†	294±62^§	295±61^§	287±62	303±66^†	294±63^§	298±64^‡	287±61
WBC, 1000s/mm³	6.38±1.98^†	6.03±1.82	6.34±2.07^§	6.07±1.83	6.47±2.06^†	6.19±1.98	6.07±1.83	6.04±1.79
Triglyceride, IU	1.49±0.75^§	1.45±0.74	1.47±0.78	1.40±0.72	1.51±0.78^†	1.49±0.76^‡	1.43±0.72	1.37±0.72
Prevalent stroke	26 (2.4)	13 (2.2)	12 (2.0)	17 (1.6))	21 (2.0)	15 (2.5)	13 (2.2)	19 (1.8)

N= the maximum number possible; some variables have lower numbers available. Fewer persons had carotid plaque information.
*Large is defined as ≥ the gender- and side-specific medians for IMT and external diameter in Table 1.
Where omnibus tests are significant, post hoc comparisons are made to the neither large IMT nor large diameter group using the Student’s t test and Chi Square test. P-values ^† <0.0005, ^‡ <0.005, ^§ 0.05.

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