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Table 1 Donor hearts rescued by stress echocardiography

From: Transplant of stunned donor hearts rescued by pharmacological stress echocardiography: a “proof of concept” report

Donor #1 #2 #3 #4 #5 #6
Age (years) 53 32 50 20 45 36
Sex Female Female Female Male Male Male
Medical history       
Brain death cause Intra-axial hemorrhage Head injury Subarachnoid hemorrhage Cardiac arrest (37 min) Head injury Subarachnoid hemorrhage
Smoking Yes Yes Yes Yes Yes Yes
Intensive Care Unit data       
Troponin T (μg/L) 0.1 0.01 0.01 15* 152* 1073*
Central Venous Pressure (mmHg) 16* - 7 - 13* 15*
Length of stay before death (days) 5 1 1 - 2 3
Noradrenaline (μg/kg/min) 0.6* Dopamine 10 0.28* 0.02 0.1 - 0.14* + dobutamine 2.8
RESTING Echo Apical Hypokinesia* Anterior-septal Hypokinesia* Apical Akinesia* Mild LVEF reduction* Septal Hypokinesia* Lateral inferior Hypokinesia*
LVEF, rest (%) 51* 46* 55 49* 60 47*
LV mass index (g/m2) 145* 89 112* 89 133* 102
WMSI, rest 1.29* 1.59* 1.65* 1 1.18* 1.26*
Stress echo       
Dipyridamole infusion (min) 6 6 4* 6 6 6
LVEF, peak (%) 60 56 59 60 75 55
WMSI, peak 1.12* 1.41* 1.71* 1 1 1.11*
Δ WMSI - 0.17 - 0.18 + 0.06* 0 - 0.18 - 0.15
ΔESP/ESVi (mmHg/mL/m2) Negative* (- 0.21) Flat* (0.08) Negative* (-1.7) Positive (+0.94) Positive (+1.2) Flat (0)
Autopsy findings Mild DCM* - CAD, 90% LAD coronary stenosis* - - -
Histology Replacing interstitial fibrosis - Coagulative necrosis, colliquative myocytolysis - - -
Heart TX - - - YES YES YES
Cold ischemia time (min)     180 172 150
Recipient       
Age/sex     56/M 48/M 55/M
Disease     Ischemic DC Congenital HD HCM
UNOS Status     2 2 2
Post-TX angiography     Normal Normal Normal
Intravascular Ultrasound-intimal thickness     - LAD focal 0.6 mm LAD
Month 1 LVEF (%)     50 62 58
Post TX endomyocardial biopsies     regular myocardium isolated foci of ischemic per transplant injury regular myocardium
Follow-up months     26 alive 9 alive 12 alive
  1. *Not Normal.