Table 3 Blood biochemistry values for each group

Gr 1 (N=14)

Gr 2 (N=14)

p (Gr 1 vs. Gr 2)

Gr 1 (N=14)

Gr 2 (N=14)

p (Gr 1 vs. Gr 2)

Gr 1 (N=8)

Gr 2 (N=8)

p (Gr 1 vs. Gr 2)

Adenine 0.5%

Controls

Adenine 0.5%

Controls

Adenine 0.5%

Controls

Creatinine (mg/dl)

0.39 ± 0.01

0.42 ± 0.01

0.078

2.33 ± 0.16 *

0.47 ± 0.01 *

< 0.001

2.01 ± 0.36 *

0.47 ± 0.01 *

< 0.001

BUN (mg/dl)

34.7 ± 1.7

33.2 ± 1.2

0.466

240.6 ± 13.0 *

33.4 ± 1.0

< 0.001

182.2 ± 28.0 *

32.3 ± 1.0

< 0.001

Ca (mg/dl)

10.6 ± 0.1

10.3 ± 0.2

0.478

7.8 ± 0.2 *

10.1 ± 0.1

< 0.001

10.0 ± 0.3 *#

10.7 ± 0.1 #

0.028

P (mg/dl)

6.6 ± 0.3

7.0 ± 0.2

0.322

17.0 ± 0.9 *

5.6 ± 0.3 *

< 0.001

6.7 ± 1.2 #

5.0 ± 0.2 *

0.234

Ca x P (mg2/dl2)

70.0 ± 3.2

72.1 ± 2.9

0.639

132.8 ± 9.2 *

56.4 ± 1.8 *

< 0.001

65.4 ± 9.4 #

52.1 ± 1.5 *

0.234

AP (U/L)

315.5 ± 9.8

303.6 ± 13.0

0.473

171.5 ± 6.5 **

133.1 ± 7.0 **

0.001

117.5 ± 2.9 **##

115.6 ± 5.6 **##

0.770

Osteocalcin

58.5 ± 2.2

54.2 ± 1.8

0.082

62.1 ± 2.2

19.8 ± 1.4 *

< 0.001

75.8 ± 2.5 *#

11.3 ± 0.4 *#

< 0.001