Differences of left ventricular systolic deformation in hypertensive patients with and without apical hypertrophic cardiomyopathy

Table 1 Comparison of clinical and electrocardiographic characteristics between hypertensive patients with and without apical hypertrophic cardiomyopathy (ApHCM)

	Hypertension with ApHCM (n = 14)	Hypertension without ApHCM (n = 14)	p
Age (years)	62 ± 11	63 ± 12	0.784
Female (%)	36	57	0.449
BMI (kg/m²)	30 (27, 32)	25 (23, 28)	0.013
Systolic blood pressure, mmHg	130 ± 12	138 ± 10	0.069
Diastolic blood pressure, mmHg	70 ± 8	77 ± 7	0.030
Heart rate (beats/min)	66 ± 11	67 ± 10	0.740
Symptoms at presentation (%)
Chest pain	29
Palpitation	7
Syncope	0
Dyspnea on exertion	43
Asymptomatic	21
NYHA class at presentation (%)
I	43
II	57
III and IV	0
Smoking (%)	50	43	1.000
Diabetes (%)	29	21	1.000
Ischemic heart disease (%)	21	14	1.000
Dyslipidemia (%)	57	36	0.449
Estimated GFR (ml/min/m²)	70 ± 25	93 ± 27	0.029
Low-density lipoprotein (mg/dL)	111 ± 42	108 ± 29	0.796
Medications (%)
β-blockers	43	43	1.000
ACEI/ARB	64	60	1.000
Calcium antagonists	86	50	0.103
Diuretics	29	7	0.326
Nitrates	21	7	0.596
Aspirin	21	36	0.678
Statins	36	36	1.000
Electrocardiography
LV hypertrophy (%)	86	21	0.002
Giant negative T waves (%)	50	0	0.006
Maximal T wave inversion (mm)	10.3 (7.3, 15.0)	0.5 (0, 2.1)	< 0.001
Corrected QT interval (ms)	446 ± 33	428 ± 17	0.081

Data are presented as means ± SD, number, or medians (25th, 75th percentiles).
ACEI = angiotensin-converting enzyme inhibitor; ARB = angiotensin II receptor blocker; BMI = body mass index; GFR = glomerular filtration rate; LV = left ventricular hypertrophy.

ISSN: 1476-7120