Control group | DM group | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline | 2 weeks | 4 weeks | 8 weeks | 12 weeks | Baseline | 2 weeks | 4 weeks | 8 weeks | 12 weeks | |
Glucose (mg/dL) | 92.34 ± 10.98 | 91.44 ± 16.56 | 93.06 ± 11.16 | 91.80 ± 14.76 | 87.66 ± 12.78 | 91.08 ± 10.08 | 409.14 ± 74.34* | 409.50 ± 81.72* | 418.5 ± 88.56* | 424.44 ± 101.7* |
HR (bpm) | 235 ± 11 | 215 ± 10 | 219 ± 13 | 230 ± 14 | 227 ± 8 | 219 ± 6 | 225 ± 18 | 241 ± 10 | 239 ± 13 | 212 ± 8 |
LA (mm) | 7.82 ± 0.61 | 7.58 ± 0.79 | 8.03 ± 0.62 | 7.69 ± 0.82 | 7.76 ± 0.47 | 7.52 ± 0.74 | 7.49 ± 0.62 | 7.78 ± 0.54 | 7.62 ± 0.50 | 11.57 ± 0.84* |
LVDd (mm) | 11.83 ± 1.10 | 11.65 ± 1.07 | 11.72 ± 1.82 | 11.47 ± 1.63 | 11.84 ± 1.40 | 11.92 ± 2.26 | 11.48 ± 0.91 | 11.57 ± 1.50 | 11.68 ± 1.34 | 13.69 ± 0.92* |
LVDs (mm) | 8.53 ± 1.35 | 8.29 ± 1.22 | 8.62 ± 1.10 | 8.71 ± 0.86 | 8.44 ± 1.52 | 8.29 ± 1.85 | 8.31 ± 1.03 | 8.49 ± 1.30 | 8.22 ± 1.53 | 10.38 ± 1.26* |
LVPW (mm) | 2.35 ± 0.43 | 2.24 ± 0.43 | 2.37 ± 0.39 | 2.45 ± 0.28 | 2.41 ± 0.51 | 2.40 ± 0.61 | 2.52 ± 0.23 | 2.48 ± 0.51 | 2.45 ± 0.59 | 3.36 ± 0.45* |
IVS (mm) | 2.29 ± 0.32 | 2.32 ± 0.36 | 2.30 ± 0.41 | 2.32 ± 0.42 | 2.25 ± 0.50 | 2.21 ± 0.62 | 2.34 ± 0.53 | 2.30 ± 0.57 | 2.33 ± 0.48 | 3.29 ± 0.39* |
EF (%) | 63.56 ± 5.53 | 60.75 ± 6.22 | 65.39 ± 3.82 | 62.77 ± 8.20 | 65.43 ± 4.82 | 62.58 ± 5.77 | 63.34 ± 4.92 | 61.89 ± 6.58 | 63.87 ± 4.52 | 44.77 ± 5.42* |
FS (%) | 31.59 ± 5.87 | 35.72 ± 4.39 | 35.01 ± 4.62 | 33.69 ± 5.28 | 32.49 ± 6.31 | 30.64 ± 5.52 | 32.41 ± 2.56 | 31.78 ± 2.69 | 32.52 ± 2.53 | 24.83 ± 4.48* |
E/A | 1.56 ± 0.51 | 1.4 ± 0.27 | 1.67 ± 0.33 | 1.55 ± 0.42 | 1.62 ± 0.22 | 1.53 ± 0.61 | 1.60 ± 0.48 | 1.57 ± 0.60 | 1.60 ± 0.23 | 0.75 ± 0.38* |
E/e’ | 3.1 ± 1.2 | 3.0 ± 0.6 | 3.0 ± 1.0 | 3.1 ± 0.8 | 3.0 ± 1.2 | 3.1 ± 1.1 | 3.3 ± 1.3 | 3.8 ± 1.8 | 6.1 ± 3.5* | 8.7 ± 2.7* |