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Table 2 Comparisons of clinical and echocardiographic parameters among morphologically classified subgroups

From: Diverse geometric changes related to dynamic left ventricular outflow tract obstruction without overt hypertrophic cardiomyopathy

 

Pure sigmoid septum

Sigmoid septum with BSH

Prominent PM

Concentric remodelling

P

(n = 14)

(n = 85)

(n = 20)

(n = 49)

Age, years

75.4 ± 9.5

72.3 ± 9.7

65.6 ± 9.7

69.9 ± 12.9

0.032

Women, n (%)

11 (79)

51 (60)

10 (50)

26 (53)

0.310

Hypertension, n (%)

14 (100)

70 (82)

16 (80)

36 (74)

0.158

Diabetes, n (%)

8 (57)

24 (28)

6 (30)

16 (33)

0.199

SBP, mmHg

124.9 ± 15.0

131.2 ± 21.0

125.3 ± 17.5

127.8 ± 22.7

0.550

DBP, mmHg

69.8 ± 10.2

72.3 ± 11.6

68.1 ± 12.9

71.0 ± 12.1

0.546

LVEDD, mm

38.7 ± 3.5

39.6 ± 4.2

39.7 ± 4.1

38.8 ± 5.7

0.742

LVESD, mm

25.4 ± 2.5

25.1 ± 3.0

25.8 ± 4.2

24.4 ± 3.6

0.361

LVEDD/BSA, mm/m2

24.9 ± 3.0

24.7 ± 3.1

22.9 ± 2.3

23.5 ± 3.1

0.028

LVESD/BSA, mm/m2

16.3 ± 1.8

15.6 ± 2.1

14.8 ± 2.0

14.7 ± 2.1

0.023

LV ejection fraction, %

66.9 ± 4.5

69.2 ± 5.7

67.9 ± 6.7

69.7 ± 5.4

0.298

Angle at end-systole, °

166.4 ± 14.6

161.0 ± 12.1

164.2 ± 10.7

162.4 ± 10.7

0.356

Angle at end-diastole, °

156.7 ± 13.4

151.3 ± 12.1

155.4 ± 12.5

151.7 ± 12.3

0.300

BST, mm

13.9 ± 1.1

18.3 ± 2.1

14.9 ± 1.4

17.4 ± 2.5

<0.001

LVMI, g/m2

74.4 ± 16.7

92.1 ± 25.3

77.2 ± 13.8

92.6 ± 30.2

0.012

LA volume index, ml/m2

27.3 ± 8.3

27.0 ± 13.0

21.9 ± 5.9

24.1 ± 8.4

0.176

E/e’

14.6 ± 5.4

14.3 ± 4.9

10.9 ± 3.3

14.5 ± 5.6

0.042

S’, cm/s

8.1 ± 2.0

8.3 ± 2.0

10.0 ± 3.1

7.8 ± 2.0

0.004

Latent DLVOTO, n (%)

14 (100)

16 (78)

17 (85)

38 (78)

0.227

LVOT PG resting , mmHg

14.8 ± 7.0

23.2 ± 23.1

17.5 ± 13.1

21.6 ± 18.0

0.393

LVOT PG Valsalva , mmHg

43.2 ± 11.8

47.4 ± 25.1

46.2 ± 13.7

47.4 ± 20.4

0.919

ΔPG, mmHg

28.4 ± 16.3

29.5 ± 18.8

30.6 ± 12.3

29.4 ± 18.0

0.988

LVESWS, g/cm

53.9 ± 10.4

51.9 ± 14.1

51.1 ± 14.3

44.5 ± 9.8

0.011

  1. DLVOTO, dynamic left ventricular outflow tract obstruction; See abbreviations in Table 1.