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Table 2 Doppler echo exercise upright treadmill/bicycle test – examples of some centers and examined diseases/conditions

From: Need for a standardized protocol for stress echocardiography in provoking subaortic and valvular gradient in various cardiac conditions

Country, town of center, type of exercise machine

Measured gradient

Clinical impact of exercise echo in UPRIGHT position

1. Portugal, Almada , treadmill

 

Stratification risk of sudden death in HCM because LVOTG is risk factor

- Hypertrophic cardiomyopathy [8, 14],

LVOT

Assessment of pharmacological and nonpharmacological methods reducing LVOTG

-Symptomatic athletes (Intra-ventricular obstruction induced by exercise in athletes with “positive screening” in medical evaluation for sports practice, [9]

LVOT

Verification of exercise-induced symptoms in relation to LVOTG

- Cardiac syndrome X [10]

LVOT

Monitoring treatment with beta blockers

- Pulmonary artery hypertension [11]

Transtricuspid

Verification of exercise-induced symptoms in relation to LVOTG

- Mitral stenosis [12]

Tranmitral

Monitoring the use of beta blockers

-Aortic stenosis [13]

Transaortic

Verification of exercise-increase of pulmonary hypertension (assessment of dyspnea)

  

Verification of exercise-induced symptoms in relation to trasmitral gradient

  

Verification of exercise-induced symptoms in relation to transaortic gradient

2. Poland, Cracow, treadmill

  

- Hypertrophic cardiomyopathy [15, 16]

LVOT

HCM see above

3. USA, Philadelphia, treadmill

  

- “healthy“ youth for cardiac evaluation due palpitations, syndrome WPW, short of breath, chest pain [5]

LVOT

Hemodynamic verification of symptoms pathophysiology

4. Sweden, Vasteras, bicycle

  

- Healthy athletes males [17]

Transaortic

Definition of normal value

5. USA, Spriengfield/ England, Liverpool, bicycle

  

- Healthy adolescent boys and girls [18]

Transaortic

Definition of normal value

6. England, London, bicycle

  

- Hypertrophic cardiomyopathy [19]

LVOT

HCM see above

- Anderson-Fabry disease [20]

LVOT

Hemodynamic assessment the effect of myocardial hypertrophy induced by storage disease

7. Spain, A Coruna, treadmill

  

- Hypertrophic cardiomyopathy [21]

LVOT

HCM see above

8. Spain, Malaga, treadmill

  

- Effort angina [22]

LVOT

Verification of exercise-induced symptoms

  

Monitoring the effect of beta blockers

9. Altavilla Vicentina, Italy, treadmill (comparison with semi physiological test protocol)

LVOT

HCM see above

- Hypertrophic cardiomyopathy [23]

  

10. Germany, Munster, bicycle

LVOT

HCM see above

- Hypertrophic cardiomyopathy [24]

  

11. Korea, Seoul, treadmill

Transaortic

Verification of exercise-induced symptoms in relation to transaortic gradient

-Aortic stenosis [25]

  

12. USA, Cleveland , treadmill

LVOT

HCM see above

-Hypertrophic cardiomyopathy [26]

  

13. Canada, Quebec, bicycle

Transprothesis- Aortic

Assessment of prosthesis function and ‘patients-prosthesis mismatch’ phenomenon

- Patients with a bioprosthesis in the aortic valve position [27] , bicycle

  

- Comparison of stentless versus stented bioprostheses in aortic valvular position [28], bicycle