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Table 5 Multivariate analysis including LA volume measurements and CHADS 2 /CHA 2 DS 2 -VASc parameters for prediction of TEE surrogate markers of stroke

From: Which method of left atrium size quantification is the most accurate to recognize thromboembolic risk in patients with non-valvular atrial fibrillation?

TEE markers of stroke Independent predictors OR CI95% p
LA Volumes + CHADS 2 parameters
LAA thrombus • Indexed LA 2P Area-Length Volume 1.026 1.009 – 1.043 0.003
  • Previous stroke/TIA 4.080 1.647 – 10.102 0.002
LAA LFV • Indexed LA 1P Area-Length Volume 1.022 1.010 – 1.034 <0.001
Dense SEC • Indexed LA 2P Area-Length Volume 1.013 0.999-1.028 0.07
• Congestive heart failure 1.968 1.024 – 3.783 0.04
  • Previous stroke/TIA 2.458 1.093 – 5.530 0.03
LA ABN • Indexed LA 2P Area-Length Volume 1.021 1.006 – 1.035 0.005
  • Congestive heart failure 2.065 1.134 – 3.758 0.02
LA Volumes + CHA 2 DS 2 -VASc parameters
LAA thrombus • Indexed LA 2P Area-Length Volume 1.028 1.010 – 1.046 0.002
  • Previous stroke/TIA 4.071 1.568 – 10.569 0.004
LAA LFV • Indexed LA 1P Area-Length Volume 1.023 1.180 – 1.037 <0.001
Dense SEC • Previous stroke/TIA 2.675 1.158 – 6.180 0.02
  • Congestive heart failure 2.308 1.180 – 4.514 0.02
LA ABN • Indexed LA 2P Area-Length Volume 1.019 1.005 – 1.034 0.009
• Congestive heart failure 2.133 1.147 – 3.966 0.02
  1. Legend: CI - confidence interval; LA – left atrial; LAA – left atrial appendage; LA ABN – left atrial abnormality; LFV – low flow velocities; OR – odds ratio; p – significance level; SEC – spontaneous echocardiographic contrast; TEE – transesophageal echocardiography; TIA – transient ischemic attack; vel – velocities; 1P – single-plane; 2P – biplane.