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Table 6 Multivariate analysis including LA area measurements and CHADS 2 /CHA 2 DS 2 -VASc parameters for prediction of TEE surrogate markers of stroke

From: Which method of left atrium size quantification is the most accurate to recognize thromboembolic risk in patients with non-valvular atrial fibrillation?

TEE markers of stroke Independent predictors OR CI95% p
LA Areas + CHADS 2 parameters
LAA thrombus • Indexed LA Area 4C 1.119 1.047 - 1.196 0.001
  • Previous stroke/TIA 3.977 1.987 – 7.959 <0.001
LAA LFV • Indexed LA Area 4C 1.141 1.075 – 1.211 <0.001
Dense SEC • Indexed LA Area 4C 1.136 1.078 – 1.198 <0.001
LA ABN • Indexed LA Area 4C 1.142 1.083 – 1.204 <0.001
  • Congestive heart failure 1.592 1.019 – 2.487 0.04
LA Areas + CHA 2 DS 2 -VASc parameters
LAA thrombus • Indexed LA Area 4C 1.133 1.058 – 1.213 <0.001
  • Previous stroke/TIA 3.932 1.917 – 8.069 <0.001
LAA LFV • Indexed LA Area 4C 1.139 1.071– 1.212 <0.001
Dense SEC • Indexed LA Area 4C 1.125 1.065 – 1.189 <0.001
  • Previous Vascular diseasea 1.930 1.180 – 3.154 0.009
LA ABN • Indexed LA Area 4C 1.147 1.086 – 1.210 <0.001
• Previous Vascular diseasea 1.581 1.010 – 2.474 0.05
  1. Legend: CI - confidence interval; LA – left atrial; LAA – left atrial appendage; LA ABN – left atrial abnormality; LFV – low flow velocities; OR – odds ratio; p – significance level; SEC – spontaneous echocardiographic contrast; TEE – transesophageal echocardiography; TIA – transient ischemic attack; vel – velocities; 4C – 4-chamber.
  2. aVascular disease is defined as having at least one of the following: myocardial infarctions, peripheral artery disease, and complex aortic plaque.