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Table 6 Multivariate analysis including LA area measurements and CHADS 2 /CHA 2 DS 2 -VASc parameters for prediction of TEE surrogate markers of stroke

From: Which method of left atrium size quantification is the most accurate to recognize thromboembolic risk in patients with non-valvular atrial fibrillation?

TEE markers of stroke

Independent predictors

OR

CI95%

p

LA Areas + CHADS 2 parameters

LAA thrombus

• Indexed LA Area 4C

1.119

1.047 - 1.196

0.001

 

• Previous stroke/TIA

3.977

1.987 – 7.959

<0.001

LAA LFV

• Indexed LA Area 4C

1.141

1.075 – 1.211

<0.001

Dense SEC

• Indexed LA Area 4C

1.136

1.078 – 1.198

<0.001

LA ABN

• Indexed LA Area 4C

1.142

1.083 – 1.204

<0.001

 

• Congestive heart failure

1.592

1.019 – 2.487

0.04

LA Areas + CHA 2 DS 2 -VASc parameters

LAA thrombus

• Indexed LA Area 4C

1.133

1.058 – 1.213

<0.001

 

• Previous stroke/TIA

3.932

1.917 – 8.069

<0.001

LAA LFV

• Indexed LA Area 4C

1.139

1.071– 1.212

<0.001

Dense SEC

• Indexed LA Area 4C

1.125

1.065 – 1.189

<0.001

 

• Previous Vascular diseasea

1.930

1.180 – 3.154

0.009

LA ABN

• Indexed LA Area 4C

1.147

1.086 – 1.210

<0.001

• Previous Vascular diseasea

1.581

1.010 – 2.474

0.05

  1. Legend: CI - confidence interval; LA – left atrial; LAA – left atrial appendage; LA ABN – left atrial abnormality; LFV – low flow velocities; OR – odds ratio; p – significance level; SEC – spontaneous echocardiographic contrast; TEE – transesophageal echocardiography; TIA – transient ischemic attack; vel – velocities; 4C – 4-chamber.
  2. aVascular disease is defined as having at least one of the following: myocardial infarctions, peripheral artery disease, and complex aortic plaque.