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Table 4 Association of cardiac mechanics with diastolic wall strain in HyperGEN

From: Diastolic wall strain: a simple marker of abnormal cardiac mechanics

Dependent variable Model 1* Model 2 Model 3 Model 4§
β-coefficient (95% CI) P-value β-coefficient (95% CI) P-value β-coefficient (95% CI) P-value β-coefficient (95% CI) P-value
GRS,% 0.02 (-0.08, 0.12) 0.71 0.12 (0.003, 0.24) 0.049 0.12 (-0.01, 0.25) 0.06 0.16 (0.00, 0.32) 0.046
GCS,% 0.13 (-0.03, 0.06) 0.58 0.05 (0.003, 0.10) 0.037 0.06 (0.01, 0.11) 0.024 0.07 (0.02, 0.14) 0.020
GLS,% 0.10 (0.07, 0.12) <0.001 0.07 (0.04, 0.10) <0.001 0.05 (0.02, 0.08) <0.001 0.07 (0.03, 0.11) 0.001
e’ velocity, cm/s 0.08 (0.07, 0.11) <0.001 0.03 (0.01, 0.05) <0.001
E/e’ ratio -0.03 (-0.06, 0.01) 0.15 0.02 (-0.03, 0.06) 0.48
  1. *Adjusted for speckle-tracking analyst, image quality, field center, and family relatedness.
  2. †Adjusted for all covariates in Model 1 plus age, sex, left ventricular mass-index, wall motion score index, and ejection fraction.
  3. ‡Includes all covariates from Model 2 with additional adjustment for average tissue e’ velocity.
  4. §Includes all covariates from Model 2 with additional adjustment for average E/e’ ratio.
  5. GRS = Global radial strain; GCS = Global circumferential strain; GLS = Global longitudinal strain; E = Early mitral inflow velocity.