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Table 4 Guideline based reference ranges for grading mr 2014 AHA/ACC Guidelines

From: Echocardiographic assessment of ischemic mitral regurgitation

2014 AHA/ACC Guidelines

Parameter

Stage A “At risk”

Stage B “Progressive”

Stage C “Asymptomatic Severe”

Stage D “Symptomatic Severe”

Valve apparatus and anatomy

CAD or cardiomyopathy, with normal valve leaflets, chords, annulus

Regional WMA with mild tethering of MV

Regional WMA ± LV dilatation with severe tethering of MV

Regional WMA ± LV dilatation with severe tethering of MV

Annular dilatation with mild loss of central coaptation

Annular dilatation with severe loss of central coaptation

Annular dilatation with severe loss of central coaptation

LV (ischemic or primary myocardial disease)

No or mild dilatation with infarct or inducible ischemia, or cardiomyopathy with LV systolic dysfunction and dilatation

Regional WMA with reduced LV systolic function ± dilatation

Regional WMA with reduced LV systolic function ± dilatation

Regional WMA with reduced LV systolic function ± dilatation

Symptoms

May be present, may respond to GDMT

May be present, may respond to GDMT

May be present, may respond to GDMT

Symptoms persist despite GDMT

EROA-CIMR (cm 2 )

< 0.2

< 0.2

≥ 0.2

≥ 0.2

Jet/LA area

No MR jet or jet area/LA area <20%

20-39%

≥ 40%

≥ 40%

VC width (cm)

< 0.3

 

≥ 0.7

≥ 0.7

Regurgitant Fraction

 

< 50%

≥ 50%

≥ 50%

Regurgitant Volume

 

< 30 mL

≥ 30 mL

≥ 30 mL