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Table 1 Main characteristics of the 368 study patients divided according to the therapeutic choice

From: Does treatment assignment influence the prognosis of patients with symptomatic severe aortic stenosis?

 

Group AVR 141 pts

Group TAVI 127 pts

Group BAV 49 pts

Group MT 51 pts

• Age (years)

72 ± 10

83 ± 8*

84 ± 9*

81 ± 7*

• Female gender (%)

52

32

49§

29*#

• Hypertension (%)

77

75

69

73

• Diabetes (%)

27

25

20

25

• Atrial fibrillation (%)

27

39

28

37

• NYHA function class (1–4 scale)

2.3 ± 0.8

2.6 ± 0.6*

2.9 ± 0.8*§

2.9 ± 0.8*§

• History of heart failure (%)

60

73*

88*§

76*

• Chronic obstructive pulmonary disease (%)

16

22

39*§

25

• Left bundle branch block (%)

8

17*

20*

16*

• Kidney disease (%)

32

65*

71*

71*

• Glomerular filtration rate (ml/min/1.73)

73 ± 26

54 ± 23*

47 ± 26*§

48 ± 28*§

• Haemoglobin (g/dl)

11.7 ± 1.8

11.9 ± 1.5

11.8 ± 1.4

11.9 ± 1.6

• Serum total colesterol (mg/dl)

162 ± 45

184 ± 47*

162 ± 29§

159 ± 38*

• Charlson comorbidity index

2.1 ± 1.5

3.5 ± 1.7*

3.5 ± 1.7*

3.7 ± 2.0*

• Katz score

2.8 ± 1.7

3.8 ± 1.9*

3.8 ± 1.9*

4.2 ± 2.2*

• EUROSCORE

16 ± 12

28 ± 18*

33 ± 18*

31 ± 20*

• LV relative wall thickness

0.55 ± 0.11

0.55 ± 0.11

0.55 ± 0.14

0.56 ± 0.13

• LV mass (gr/m2)

209 ± 56

217 ± 59

541 ± 72*§°

207 ± 71#

• LV end-diastolic diameter (mm)

50.7 ± 0.8

50.7 ± 0.8

52.3 ± 0.9

50. ± 0.9

• LV end-diastolic volume (ml)

139 ± 69

141 ± 69

155 ± 79

132 ± 67

• LV ejection fraction (%)

53 ± 11

51 ± 12

41 ± 11*§°

50 ± 10#

• Pulmonary artery systolic pressure (mmHg)

38 ± 11

43 ± 14*

47 ± 15*§°

43 ± 12*

• Aortic valve area (cm2/m2)

0.41 ± 0.10

0.35 ± 0.08*°

0.34 ± 0.12*°

0.42 ± 0.13§#

• Trans valve area peak gradient (mmHg)

79 ± 24

86 ± 22*

71 ± 27§

76 ± 24§

• Biscuspid aortic valve (%)

8

1*

4

6

• Beta-blockers (%)

42

28*

21*

35

• ACE-inhibitors/ARBs (%)

65

67

37*§°

65#

• Diuretics (%)

70

83*

95*

75

• Statins (%)

46

53

45

63

• Warfarin (%)

80

60*

55*

45*

  1. ACE = angiotensin-converting enzyme; ARB = angiotensine receptor blockers; AVR = traditional surgical aortic valve replacement; BAV-baloon aortic valvuloplasty; LV = left ventricular; MT = Medical Therapy; HYHA = New York Heart Associations; TAVI = tanscatheter aortic valve implentaions..
  2. p & 0.05 vs AVR = *; vs TAVI = §; vs BAV = #; vs MT = °.
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Cardiovascular Ultrasound

ISSN: 1476-7120

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