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Table 1 Main characteristics of the 368 study patients divided according to the therapeutic choice

From: Does treatment assignment influence the prognosis of patients with symptomatic severe aortic stenosis?

  Group AVR 141 pts Group TAVI 127 pts Group BAV 49 pts Group MT 51 pts
• Age (years) 72 ± 10 83 ± 8* 84 ± 9* 81 ± 7*
• Female gender (%) 52 32 49§ 29*#
• Hypertension (%) 77 75 69 73
• Diabetes (%) 27 25 20 25
• Atrial fibrillation (%) 27 39 28 37
• NYHA function class (1–4 scale) 2.3 ± 0.8 2.6 ± 0.6* 2.9 ± 0.8*§ 2.9 ± 0.8*§
• History of heart failure (%) 60 73* 88*§ 76*
• Chronic obstructive pulmonary disease (%) 16 22 39*§ 25
• Left bundle branch block (%) 8 17* 20* 16*
• Kidney disease (%) 32 65* 71* 71*
• Glomerular filtration rate (ml/min/1.73) 73 ± 26 54 ± 23* 47 ± 26*§ 48 ± 28*§
• Haemoglobin (g/dl) 11.7 ± 1.8 11.9 ± 1.5 11.8 ± 1.4 11.9 ± 1.6
• Serum total colesterol (mg/dl) 162 ± 45 184 ± 47* 162 ± 29§ 159 ± 38*
• Charlson comorbidity index 2.1 ± 1.5 3.5 ± 1.7* 3.5 ± 1.7* 3.7 ± 2.0*
• Katz score 2.8 ± 1.7 3.8 ± 1.9* 3.8 ± 1.9* 4.2 ± 2.2*
• EUROSCORE 16 ± 12 28 ± 18* 33 ± 18* 31 ± 20*
• LV relative wall thickness 0.55 ± 0.11 0.55 ± 0.11 0.55 ± 0.14 0.56 ± 0.13
• LV mass (gr/m2) 209 ± 56 217 ± 59 541 ± 72*§° 207 ± 71#
• LV end-diastolic diameter (mm) 50.7 ± 0.8 50.7 ± 0.8 52.3 ± 0.9 50. ± 0.9
• LV end-diastolic volume (ml) 139 ± 69 141 ± 69 155 ± 79 132 ± 67
• LV ejection fraction (%) 53 ± 11 51 ± 12 41 ± 11*§° 50 ± 10#
• Pulmonary artery systolic pressure (mmHg) 38 ± 11 43 ± 14* 47 ± 15*§° 43 ± 12*
• Aortic valve area (cm2/m2) 0.41 ± 0.10 0.35 ± 0.08*° 0.34 ± 0.12*° 0.42 ± 0.13§#
• Trans valve area peak gradient (mmHg) 79 ± 24 86 ± 22* 71 ± 27§ 76 ± 24§
• Biscuspid aortic valve (%) 8 1* 4 6
• Beta-blockers (%) 42 28* 21* 35
• ACE-inhibitors/ARBs (%) 65 67 37*§° 65#
• Diuretics (%) 70 83* 95* 75
• Statins (%) 46 53 45 63
• Warfarin (%) 80 60* 55* 45*
  1. ACE = angiotensin-converting enzyme; ARB = angiotensine receptor blockers; AVR = traditional surgical aortic valve replacement; BAV-baloon aortic valvuloplasty; LV = left ventricular; MT = Medical Therapy; HYHA = New York Heart Associations; TAVI = tanscatheter aortic valve implentaions..
  2. p & 0.05 vs AVR = *; vs TAVI = §; vs BAV = #; vs MT = °.