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Table 1 Comparison of echocardiography and MRI findings between Anderson-Fabry and hypertrophic cardiomyopathy.

From: Reduced coronary flow reserve in Anderson-Fabry disease measured by transthoracic Doppler echocardiography

  Anderson-Fabry HCM
LVH pattern Concentric>Asymmetric Asymmetric>Concentric
Resting LVOT gradient Rare 25–30%
Massive LVH> 30 mm Rare 10–15%
LV diastolic dysfunction (tissue Doppler, strain rate)   
With LVH Yes Yes
Without LVH (genotype +) Yes Yes
LV systolic dysfunction More frequent especially in older males  
Magnetic resonance
Most common site of late-enhancement (if present) Infero-lateral segment Ventricular junction, Multi-focal
  1. LVH- left ventricular hypertrophy; LVOT – left ventricular outflow tract