Figure 3

Repair process of CN. A) early monocytes infiltration which later, becomes extensive especially in large necrotic foci (B). It can be misinterpreted as lymphocytic myocarditis. This macrophagic reaction results in empty sarcolemmal tubes with numerous macrophages often loaded with lipofuscin and normal intramural vessels (C). The end result is a focal or plurifocal or confluent fibrosis (D). Microfocal fibrosis as result of necrosis of few myocells (E) can be confused with proliferation of collagen matrix. F) wavyness of normal myofiber around hypercontracted elements. G) all stages of CN in human pheochromocytoma.