Avascular area of an infarct. By plastic cast (A anterior, B posterior view) or postmortem angiogram (C) the infarcted zone (arrow) lacks of intramural vessel injection ("avascular area"). Stretching of the necrotic myocardium and secondary vascular damage with wall degeneration and thrombosis (D), explain this vascular "sequestration" which occurs in early phase. This may indicate a blockage without possibility of therapeutical intervention via blood flow within the infarcted myocardium. Note that the avascular area in this AMI case documented histologically, depended from LAD without evidence of occlusion or severe stenosis. The occluded vessel (arrow) was (B) the RCA, the distal part of which was filled by numerous anastomoses. No myocardial damage was seen in its territory. By dissection even an expert pathologist, the diagnosis could be of myocardial infarction following occlusion of the RCA. E) obliterative intimal hyperplasia in arterioles around a seven days old infarct with early repair process.