Cohort Sample N = 8163‡ | Subsets* of Cohort Sample | ||||
---|---|---|---|---|---|
Pre-existing Disease N = 591‡ | High Risk N = 6175‡ | Low Risk N = 1397‡ | p-value | ||
Age (mean, std) | 54.2 (5.7) | 56.5 (5.3) | 54.4 (5.7) | 52.2 (5.4) | <0.0001 |
Male Gender (%) | 44.8 | 64.3 | 44.8 | 36.7 | <0.0001 |
Black Race (%) | 25.5 | 25.5 | 28.7 | 12.3 | <0.0001 |
Height in cm (mean, std) | 168.5 (9.3) | 170.4 (8.9) | 168.4 (9.3) | 168.0 (9.0) | <0.0001 |
Stroke (%) | 2.4 | 33.7† | 0§ | 0§ | NA |
Coronary Heart Disease | 5.2 | 72.2† | 0§ | 0§ | NA |
Plaque or Shadowing | 35.7 | 52.7 | 44.0† | 0§ | 0.0002 |
Smoker (%) | |||||
Current | 26.9 | 29.6 | 32.8† | 0§ | 0.0783§§ |
Former | 31.8 | 43.8 | 28.7 | 40.5 | |
Never | 41.3 | 26.6 | 38.5 | 59.5 | |
Cigarette Years for Current Smokers (mean, std) | 681.9 (438.9) | 845.3 (532.4) | 667.7 (427.1) | N/A | <0.0001 |
Drinker (%) | |||||
Current | 56.3 | 48.6 | 55.4 | 63.4 | <0.0001§§ |
Former | 19.3 | 31.5 | 19.1 | 14.9 | |
Never | 24.4 | 20.0 | 25.5 | 21.7 | |
Ethanol g/wk for Current Drinkers (mean, std) | 76.3 (119.1) | 87.8 (125.5) | 81.1 (125.8) | 54.1 (81.9) | <0.0001 |
Diabetes (%) | 11.4 | 22.3 | 12.9† | 0§ | <0.0001 |
Hypertension (%) | 35.5 | 54.3 | 41.7† | 0§ | <0.0001 |
Cholesterol Medication Use (%) | 3.0 | 6.5 | 3.3† | 0§ | <0.0001 |
Body Mass Index (mean, std) | 27.7 (5.3) | 28.2 (5.4) | 28.3 (5.5)† | 24.7 (2.8) | <0.0001 |
Systolic Blood Pressure mm Hg (mean, std) | 121.4 (18.7) | 122.7 (21.6) | 123.5 (19.0)† | 111.5 (12.0) | <0.0001 |
Diastolic Blood Pressure mm Hg (mean, std) | 73.7 (11.3) | 72.6 (12.5) | 74.8 (11.5)† | 69.6 (8.5) | <0.0001 |
LDL Cholesterol mg/dl (mean, std) | 138.2 (39.5) | 145.2 (39.5) | 142.5 (40.3)† | 116.2 (26.0) | <0.0001 |
HDL Cholesterol mg/dl (mean, std) | 51.5 (17.0) | 44.6 (15.9) | 50.4 (16.2) | 59.2 (18.7) | <0.0001 |
Fibrinogen (mean, std) | 304.3 (65.3) | 321.9 (72.0) | 308.6 (65.0) | 277.5 (55.5) | <0.0001 |
White Blood Count (thousands) (mean, std) | 6.2 (2.1) | 6.7 (3.3) | 6.3 (2.0) | 5.4 (1.5) | <0.0001 |