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Table 2 Beta coefficients and 95% confidence intervals (CI) for multivariable linear regression models with CCA diameter as the outcome after adjustment for basic covariates and after adding atherosclerotic risk factors.* Both models included interaction terms allowing determination of effects of age in subsets of varying atherosclerosis severity, the Atherosclerosis Risk in Communities (ARIC) Limited Data Set, 1987–1989

From: Common carotid arterial interadventitial distance (diameter) as an indicator of the damaging effects of age and atherosclerosis, a cross-sectional study of the Atherosclerosis Risk in Community Cohort Limited Access Data (ARICLAD), 1987–89

  Basic Model N = 8163 Full Model N = 8163
  Beta (95% CI) p-value Beta (95% CI) p-value
Main effects     
   Male gender 0.492 (0.439, 0.545) <0.0001 0.435 (0.384, 0.486) <0.0001
   Black race/ethnicity 0.190 (0.149, 0.231) <0.0001 0.087 (0.044, 0.130) <0.0001
   Height (cm) 0.020 (0.018, 0.022) <0.0001 0.023 (0.021, 0.025) <0.0001
   Current smoking -   0.154 (0.107, 0.201) <0.0001
   Current drinking -   -0.038 (-0.075, -0.001) 0.0485
   Cigarette years of smoking (in 100's) -   0.019 (0.015, 0.023) <0.0001
   Ethanol (100 grams/week) -   0.039 (0.021, 0.057) <0.0001
   BMI -   0.025 (0.021, 0.029) <0.0001
   Systolic BP -   0.017 (0.015, 0.019) <0.0001
   Diastolic BP -   -0.013 (-0.015, -0.011) <0.0001
   Fibrinogen -   0.0002 (0.0000, 0,0004) 0.0335
   Age (1 year of age) 0.028 (0.020, 0.036) <0.0001 0.017 (0.009, 0.025) <0.0001
Additional diameter increase per year of age     
   Among Diseased Subset 0.018 (0.004, 0.032)§ 0.0139 0.013 (-0.001, 0.027)§ 0.0611
   Among Risk Factor Subset 0.011 (0.003, 0.019)§§ 0.0096 0.011 (0.003, 0.019)§§ 0.0101
  1. * Basic model independent variables = age, race, gender, height, dummy variables for disease severity, and interaction terms between age-disease severity dummy variables. Full model added variables = BMI, systolic and diastolic blood pressures, current smoker status, cigarette years of smoking in hundreds, current drinker status and grams of ethanol usually consumed per week in 100 g, fibrinogen value.
  2. Beta indicates the expected difference in millimeters of CCA diameter associated with the presence of each categorical variable and for each unit increase of continuous variables.
  3. Beta indicates the expected difference in millimeters of CCA diameter for each year of older age in the low risk subset.
  4. §-§§Betasindicate the expected difference in millimeters of CCA diameter associated with each year of age among the diseased (§) and risk factor or high risk (§§) subsets.