Comparison of tricuspid inflow and superior vena caval Doppler velocities in acute simulated hypovolemia: new non-invasive indices for evaluating right ventricular preload

Table 1 Effects of LBNP on hemodynamic and Doppler indices in healthy young men (Mean ± SD , n = 12 )

LBNP (mmHg)	HR (bpm)	SAP (mmHg)	DAP (mmHg)	SVC(cm/s)			TV(cm/s)		Ratio Indices
				S	D	AR	E	A	S/D	E/A
Baseline	67 ± 10	128 ± 10	77 ± 5	59.6 ± 12.3	38.0 ± 7.1	22.8 ± 5.0	71.2 ± 8.1	41.0 ± 7.8	1.57 ± 0.19	1.79 ± 0.38
-10	69 ± 10	128 ± 9	78 ± 5	50.2 ± 14.2*	33.8 ± 7.7	19.2 ± 4.4*	67.9 ± 8.9	41.6 ± 7.2	1.47 ± 0.18	1.67 ± 0.35
-20	70 ± 7	126 ± 9	77 ± 4	50.0 ± 11.3^‡	30.1 ± 6.9*	16.3 ± 4.4^‡	65.3 ± 9.0	41.0 ± 6.5	1.35 ± 0.14^†	1.62 ± 0.29
-30	74 ± 10	125 ± 10	78 ± 6	36.7 ± 9.3^‡	28.6 ± 7.6^†	14.0 ± 4.4^‡	63.0 ± 9.1*	41.7 ± 6.8	1.29 ± 0.14^‡	1.54 ± 0.32
-40	78 ± 8^†	123 ± 9	77 ± 5	31.0 ± 6.9^‡	25.6 ± 5.5^‡	12.0 ± 3.6^‡	60.9 ± 9.5^†	42.0 ± 7.1	1.23 ± 0.20^‡	1.48 ± 0.32*
-50	83 ± 8^‡	119 ± 8*	76 ± 5	28.0 ± 6.7^‡	23.5 ± 4.6^‡	10.2 ± 3.0^‡	58.3 ± 9.7^†	43.7 ± 6.0	1.19 ± 0.16^‡	1.36 ± 0.31^†
-60	94 ± 9^‡	118 ± 8^†	79 ± 6	26.1 ± 5.9^‡	20.3 ± 4.1^‡	8.4 ± 2.4^‡	55.6 ± 10.2^‡	45.3 ± 7.6	1.30 ± 0.23^‡	1.26 ± 0.32^‡
Release	60 ± 10*	130 ± 9	77 ± 5	62.3 ± 12.5	40.7 ± 7.3	25.1 ± 5.1	72.4 ± 7.8	41.0 ± 7.8	1.53 ± 0.21	1.74 ± 0.35

"Release" refers to data measured at 3-min after LBNP release to baseline (0 mmHg); LBNP=lower body negative pressure; HR=heart rate; SAP=systolic arterial pressure; DAP=diastolic arterial pressure; SVC=superior vena cava; TV=tricuspid valve; S= systolic forward velocity of SVC; D= diastolic forward velocity of SVC; AR= atrial resversal velocity of SVC; E=early transtricuspid filling velocity; A=late transtricuspid filling velocity. *P < 0.05; † P < 0.01; ‡ P < 0.001; compared to Baseline.

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