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Table 1 Aortic valve stenosis progression.

From: Is there a role of statins in the prevention of aortic biological prostheses degeneration

Author (year of publication) [reference]

N. patient (receiving statins)

Follow-up (months)

Mean age (years)

Prospective/retrospective

Randomized/non randomized

CAD (%)

A. Vel. max (m/sec)

Positive effect of statin

Aronow et al. (2001) [5]

180 (62)

33

82 ± 5

retrospective

non-randomized

NA

NA

Yes

Novaro et al. (2001) [6]

174 (57)

21

68 ± 12

retrospective

non-randomized

59

2,65

Yes

Bellamy et al. (2002) [7]

156 (38)

44

77 ± 12

retrospective

non-randomized

35

2,95

Yes

Rosenhek et al. (2004) [26]

211 (50)

24

70 ± 10

retrospective

non-randomized

27

3,96

Yes

Antonini-Canterin et al. (2005) [25]

242 (121)

48

67 ± 9

retrospective

non-randomized

46

2,45

No

Cowell et al. (2005) [15]

134 (65)

25

68 ± 11

prospective

randomized

20

3,42

No

  1. Authors of the studies with years follow-up, mean age, cardiovascular risk factors, peak aortic velocity and the presence of a positive effect of statins on aortic valve stenosis progression.