Journal (Year of Publication)
Type of study and Number of patients
Pigula F 
Journal of Thoracic Cardiovascular Surgery (2000)
Observational on 6 neonates
Significant decreases are shown in both cerebral blood volume and oxygen saturation in children who underwent repair with DHCA as compared with children with RLFP.
Andropulos D 
Journal of Thoracic Cardiovascular Surgery (2002)
Observational on 34 neonates
The use of TCD is able to maintain cerebral oxygen saturations and blood flow velocities within 10% of baseline, in order to prevent cerebral hyperperfusion during periods with high NIRS saturation values.