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Table 2 Baseline cross-sectional associations between B-mode ultrasound RCCA measures and prevalent MI and the discrimination of the respective models in the developmental and test data sets of the ARICLAD, 1987–89

From: Common carotid artery wall thickness and external diameter as predictors of prevalent and incident cardiac events in a large population study

  

Vascular Measures' Association with Prevalent MI

Discrimination of Prevalent MI

    

Men, Data Sets

Women, Data Sets

Model

RCCA

Measure

Men

N = 5061

OR (95% CI)*

Women

N = 6164

OR (95% CI)*

Development

N = 3215

AUC

Test

N = 1846

AUC

Development

N = 3910

AUC

Test

N = 2254

AUC

1

IMT

1.32 (1.22–1.43)

1.36 (1.18–1.55)

0.586

0.616

0.631

0.632

2

IMT

1.23 (1.13–1.34)

1.21 (1.02–1.42)

0.640

0.676

0.681

0.682

3

IMT

1.17 (1.07–1.28)

1.17 (0.99–1.38)

0.753

0.749

0.741

0.690

1

Diameter

1.29 (1.16–1.43)

2.10 (1.73–2.55)

0.551

0.614

0.689

0.687

2

Diameter

1.21 (1.08–1.35)

1.81 (1.47–2.24)

0634

0.680

0.717

0.719

3

Diameter

1.14 (1.02–1.28)

1.73 (1.40–2.14)

0.750

0.747

0.766

0.718

1

Wall area

1.36 (1.25–1.48)

1.60 (1.38–1.86)

0.585

0.638

0.678

0.675

2

Wall area

1.27 (1.16–1.39)

1.40 (1.19–1.66)

0.639

0.684

0.700

0.697

3

Wall area

1.20 (1.09–1.32)

1.35 (1.14–1.60)

0.753

0.751

0.753

0.700

Model

Two Measures

Men

OR (95% CI)

Women

OR (95% CI)

Men

Women

    

Developmental

Test

Developmental

Test

1

IMT + Diameter

1.27 (1.16–1.38)

1.16 (1.04–1.30)

1.09 (0.91–1.3)

2.00 (1.61–2.49)

0.586

0.644

0.696

0.687

2

IMT + Diameter

1.19 (1.09–1.31)

1.13(1.01–1.27)

1.02 (0.84–1.24)

1.80 (1.43–2.25)

0.640

0.689

0.719

0.717

3

IMT + Diameter

1.15 (1.05–1.26)

1.09 (0.97–1.23)

1.01 (0.83–1.22)

1.73 (1.37–2.17)

0.753

0.750

0.767

0.716

  1. OR: odds ratio for 1 standard deviation increment of the vascular measure
  2. CI: confidence interval
  3. Model 1: vascular measure(s) only; Model 2: add age, race, and height; Model 3 for men: age, race, diabetes mellitus, systolic blood pressure, fibrinogen, HDL and LDL cholesterol, and hypertension; Model 3 for women: age, race, current drinking status, HDL cholesterol, diastolic blood pressure and white blood count.