Table 4 Among men, the overall and age-specific risks associated with RCCA B-mode ultrasound vascular measures and the discrimination for the overall models in the developmental and test data sets of the ARICLAD, 1987–99
| Â | Â | Risk for Incident Cardiac Events | Model Discrimination for All Ages | |||
|---|---|---|---|---|---|---|
Model | RCCA Measure | All N = 4714 | Age ≤ 54 N = 2415 | Age > 54 N = 2299 | Development N = 2995 | Test N = 1719 |
| Â | Â | HR (95% CI) | HR (95% CI) | HR (95% CI) | AUC | AUC |
1 | IMT | 1.26 (1.17–1.34) | 1.36 (1.23–1.50) | 1.14 (1.04–1.25) | 0.597 | 0.606 |
2 | IMT | 1.20 (1.11–1.29) | 1.35 (1.22–1.50) | 1.11 (1.01–1.23) | 0.626 | 0.633 |
3 | IMT | 1.10 (1.02–1.18) | 1.22 (1.10–1.36) | 1.04 (0.94–1.14) | 0.718 | 0.710 |
1 | diameter | 1.36 (1.24–1.49) | 1.40 (1.21–1.62) | 1.26 (1.13–1.42) | 0.599 | 0.608 |
2 | diameter | 1.30 (1.18–1.42) | 1.40 (1.20–1.62) | 1.24 (1.10–1.40) | 0.629 | 0.633 |
3 | diameter | 1.19 (1.08–1.32) | 1.28 (1.09–1.49) | 1.16 (1.02–1.31) | 0.719 | 0.713 |
1 | Wall area | 1.33 (1.24–1.42) | 1.45 (1.30–1.61) | 1.20 (1.09–1.29) | 0.614 | 0.636 |
2 | Wall area | 1.26 (1.17–1.37) | 1.41 (1.29–1.61) | 1.17 (1.06–1.29) | 0.636 | 0.653 |
3 | Wall area | 1.15 (1.06–1.24) | 1.29 (1.15–1.45) | 1.08 (0.98–1.20) | 0.721 | 0.711 |
Model | Double vascular | All | Age ≤ 54 | Age >54 |  |  |
1 | IMT + diameter | 1.18 (1.09–1.27) 1.27 (1.15–1.40) | 1.28 (1.14–1.44) 1.26 (1.07–1.48) | 1.08 (0.97–1.20) 1.23 (1.09–1.39) | 0.616 | 0.636 |
2 | IMT + diameter | 1.13 (1.05–1.23) 1.24 (1.12–1.37) | 1.27 (1.14–1.43) 1.26 (1.07–1.49) | 1.05 (0.95–1.18) 1.22 (1.08–1.38) | 0.637 | 0.652 |
3 | IMT + diameter | 1.06 (0.98–1.15) 1.17 (1.06–1.29) | 1.17 (1.04–1.32) 1.20 (1.02–1.42) | 1.01 (0.91–1.12) 1.16 (1.02–1.31) | 0.721 | 0.713 |