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Table 1 Clinical studies that achieved a significant relation of spectral tissue Doppler E/E' ratio with invasive pulmonary capillary wedge pressure or mean left ventricular diastolic pressure in patients with preserved left ventricular systolic function

From: Current clinical applications of spectral tissue Doppler echocardiography (E/E' ratio) as a noninvasive surrogate for left ventricular diastolic pressures in the diagnosis of heart failure with preserved left ventricular systolic function

Reference Population study Number of patients r-value LV ejection fraction
Sundereswan (1998)48 Heart transplants 50 0.8 (L) 56 ± 12%
Nagueh (1998)49 ICU/Catheterism 49 0.72 (L) > 45%
Nagueh (1999)50 HCM 35 0.76 (L) > 50%
Sohn (1999)51 Atrial fibrillation 27 0.79 (S) 53 ± 11%
Ommen (2000)45 Catheterism 64 0.47 (S) > 50%
Kim (2000)52 Catheterism 167 0.74 (S) > 50%
Gonzalez (2002)53 ICU 32 0.54 (L) > 50%
Rivas-Gotz (2003)54 ICU/Catheterism 55 0.7 (L) > 50%
Bruch (2004)57 Aortic stenosis 23 0.75 (S) 59 ± 11%
Bruch (2005)58 Diastolic HF 28 0.56 (A) > 45%
Hadano (2005)59 Catheterism 65 0.54 (L) > 50%
Paelinck (2005)60 Chronic hypertension 18 0.85 (S) 58 ± 7%
  1. Catheterism: clinically indicated catheterism; HCM: hypertrophic cardiomyopathy; HF: heart failure; ICU: intensive care unit; LV: left ventricular; (L): lateral E/E' ratio; (S): septal E/E' ratio; (A): average E/E' ratio.