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Table 4 Clinical studies that investigated the accuracy of the spectral tissue Doppler E/E' for the diagnosis of acute congestive heart failure on admission before tailored therapy.

From: Current clinical applications of spectral tissue Doppler echocardiography (E/E' ratio) as a noninvasive surrogate for left ventricular diastolic pressures in the diagnosis of heart failure with preserved left ventricular systolic function

Reference

Population study

Number of patients

Sensitivity-Specificity

Threshold value for E/E'

Dokainish97

NYHA II to IV

LVEF < 50%

76

92% – 72%

Average E/E' > 15

Dokainish97

NYHA II to IV

LVEF > 50%

46

79% – 93%

Average E/E' > 15

Arques98

Acute dyspnea at rest

LVEF > 45%

70

80% – 94.3%

76.7% – 91.4%

Average E/E' > 11.5

Septal E/E' > 13

Arques99

Acute dyspnea at rest

LVEF > 50%, BNP 100–400 pg/ml

34

88.2% – 76.5%

76.5% – 88.2%

Average E/E' > 10.1

Septal E/E' > 13

Arques100

Acute dyspnea at rest, elderly

LVEF > 50%, atrial fibrillation

41

81.8% – 89.5%

Septal E/E' > 13

Arques104

Acute dyspnea

LVEF > 50%, hypertension

40

77.8% – 100%

Lateral E/E' > 11

Huang105

Acute dyspnea

LVEF < 50%

-*

70.8% – 100%

Average E/E' > 16

Huang105

Acute dyspnea

LVEF > 50%

-*

88.9% – 82.9%

Average E/E' > 11

  1. BNP: B-type natriuretic peptide; LVEF: left ventricular ejection fraction;*: overall population of 92 patients.