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Table 3 Coefficients of variation from CIMT reproducibility studies

From: Carotid intima-medial thickness measured on multiple ultrasound frames: evaluation of a DICOM-based software system

  

Coefficient of Variation

Study

n

Inter-sonographer

Intra-sonographer

Inter-observer

Intra-observer

Manual Measurement (callipers on ultrasound screen)

Salonena [27]

10

10.5

5.4

-

-

Bonithon-Koppb [35]

81

-

-

9.0

-

Schillacic [36]

128

-

-

7.3

5.0

Raitakari [37]

60/113

-

6.4

5.2

-

Kobayashi [38]

12

-

4.2

-

-

Software 1 (arterial interfaces traced manually by observer)

Wendelhag [39]

74

10.2

-

-

-

Botsb [40]

80

8.1

-

4.5

-

Persson [41]

43

11.4

8.0

-

-

Touboulb [16]

14

12.5

8.6

-

-

Rileya, b, c [42]

453

7.6

6.1

6.8

3.8

Wendelhag [14, 43]

50

-

10.6

2.8

3.8

Liang [44]

50

-

2.8

-

-

Nowak [45]

-

-

9.0

-

-

Baldassarre [46]

22

-

4.1

-

-

Baldassarred [46]

22

-

2.1

-

-

Becker [47]

7

-

11.0

-

-

Orenb, c [48]

21

5.4

-

-

-

Software 2 (automated edge-detection)

Selzer [18]

8

3.9

4.3

-

-

Blankenhorn [49]

20

-

-

3.1

3.0

Gariepy [17]

11

-

4.3

-

-

Adams [20]

35/100

6.0

-

2.5

-

Wendelhag [14]

50

-

-

1.4

-

Stensland-Bugge [26]

75

9.0

5.9

-

1.3

McQuillan [22]

30

5.9

2.9

-

-

Selzer [28]

24

-

3.5

  

Kennedyc [50]

144

-

-

6.8

6.7

Fathi [51]

288

-

-

-

5.0

Gepner [12]e

40

-

-

-

3.1

Gepner [12]f

40

-

-

-

7.8

de Bree [52]

80

6.5

-

-

-

Potter

30

6.8

5.7

-

2.1

Software 3 (current study)

Potterg

30

6.5

6.8

3.5

2.4

Potterh

30

7.0

6.2

5.1

1.5

  1. CV indicates co-efficient of variation; CIMT, carotid intima-media thickness; CVD, cardiovascular disease; CCA, common carotid artery.
  2. a Maximum rather than mean CCA used for reproducibility study
  3. b CVs calculated from reported data (SD of absolute difference/mean CIMT *100)
  4. cCIMT calculated as average of near and far wall of CCA
  5. d Digital ultrasound system
  6. eExperienced observer
  7. fNovice observer
  8. gSix-frame protocol
  9. hSixty frame measurement protocol
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Cardiovascular Ultrasound

ISSN: 1476-7120

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