Table 2 Main studies evaluating the accuracy of standard Doppler echocardiography in detecting AAR
From: Usefulness and limitations of transthoracic echocardiography in heart transplantation recipients
Authors | N. of patients | Method/Parameter | Sensitivity | Specificity |
|---|---|---|---|---|
Desruennes M, J Am Coll Cardiol 1988 | 55 | Standard Doppler, PHT decrease (20%) | 88% | 87% |
Simmonds MB, Circulation 1992 | 30 | Standard Doppler, superior vena caval SFFV ≤ 17 cm/s | 100% | 80% |
Morocutti G, J Heart Lung Transplant 1995 | 18 | Standard Doppler, PHT ≤ 55 ms PHT ≤ 60 ms | 69% 62% | 76% 83% |
Mouly-Bandini A, Transpl Int 1996 | 23 | Standard Doppler, IVRT decrease ≥ 20% | 45% | - |
Angermann GE, Circulation 1997 | 52 | M-mode and 2D parameters | 40–55% | 84–87% |
Stengel SM, Heart 2001 | 141 | Pulsed Tissue Doppler. Am of mitral annulus < 8.7 cm/s | 82% | 53% |
Vivekananthan K, Am J Cardiol 2002 | 20 | Standard Doppler, MPI | 90% | 90% |
Sun JP, J Heart Lung Transplant 2005 | 223 183 | Standard Doppler echo ≥ 2 among PE, IVRT > 90 ms, E/A > 1.7 post HT ≤ 6 months post HT > 6 months | 57% 60% | 54% 93% |