Effects of cognac on coronary flow reserve and plasma antioxidant status in healthy young men

Table 2 Effects of cognac on coronary flow velocity during CPT (hyperemia to baseline ratio) and coronary flow velocity reserve (CFR) in the LAD

		Before drinking	Before drinking vs. Moderate dose	Before drinking vs High dose	Trend
Cognac	CPT	1.21 ± 0.26	-0.12 (-0.29 – 0.06) NS	-0.03 (-0.19 – 0.13) NS	P = 0.91
N = 18	CFR	4.4 ± 0.8	-0.29 (-0.83 – 0.24) NS	0.15 (-0.39 – 0.68) NS	P = 0.71
		Control 1	Control 2
Control	CPT	1.23 ± 0.20	0.01 (-0.10 – 0.13) NS		P = 0.64
N = 16	CFR	4.5 ± 1.0	-0.45 (-0.99 – 0.09) NS		P = 0.85

Moderate and high dose correspond the amount of 0.5 g/kg and 1.0 g/kg ethanol, respectively. Data before drinking are presented mean ± SD. Data in the other columns are presented as the difference between the means (95% confidence intervals). The corresponding P value is from repeated analysis of variance. P-values indicating trend were calculated using the repeated measures regression analysis. Control 1 correspond the first measurement on control day. Control 2 correspond the measurement carried out 2 h after Control 1. N = number of subjects in a group. NS = not significant (P > 0.05)

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