Table 1 Inclusion criteria

Age between 35 and 75 years

Presence of blood pressure values higher than 130/85 mmHg and/or dyslipidemia (defined according to the ESH/ESC guidelines)

Absence of previous or concomitant drug treatments

Absence of secondary hypertension and monogenic dyslipidemia

Absence of serious pulmonary, renal, hepatic, gastrointestinal, endocrine, immunologic, neoplastic diseases

Absence of previous cardiovascular diseases

Absence of diabetes mellitus

Absence of pregnancy