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Table 1 General characteristics of the study groups. Comparison of clinical and echocardiographic features among the four study groups.

From: Acute effects of caffeine and cigarette smoking on ventricular long-axis function in healthy subjects

 

Controls

Coffee assumption

Cigarette smoking

Coffee assumption + cigarette smoking

ANOVA P value

Age (years)

24.1 ± 1.7

25.3 ± 4.3

24.9 ± 2.7

23.6 ± 2.5

0.68

Male gender (n)

6 (60%)

9 (60%)

6 (40%)

9 (60%)

0.68

BMI (Kg/m2)

20.2 ± 2.1

20.7 ± 5.5

21.0 ± 1.7

22.0 ± 2.4

0.38

Coffees (n/die)

-

2.5 ± 1.1

-

3.0 ± 2.4

0.28*

Cigarettes (n/die)

-

-

8.4 ± 5.3

11.7 ± 5.1

0.09*

Years of smoking (n)

-

-

7.5 ± 3.8

8.1 ± 2.7

0.66*

SBP (mmHg)

116.0 ± 8.1

125 ± 9.6

116.7 ± 12.8

122.3 ± 2.5

0.11

DBP (mmHg)

75.0 ± 5.8

76.7 ± 9.6

75.0 ± 11.2

79.7 ± 7.9

0.50

Heart rate (bpm)

74.9 ± 10.0

74.5 ± 10.6

72.7 ± 11.4

66.1 ± 9.4

0.15

O 2 saturation (%)

97.5 ± 1.2

97.6 ± 0.7

97.9 ± 0.7

97.5 ± 0.9

0.77

LVEDV (ml)

89.0 ± 28.2

99.7 ± 28.3

89.4 ± 14.2

92.9 ± 29.5

0.84

Ejection fraction (%)

67.4 ± 3.2

64.8 ± 3.6

64.2 ± 5.5

63.8 ± 4.8

0.14

Stroke volume (ml)

60.0 ± 18.5

66.4 ± 23.0

57.8 ± 5.5

59.2 ± 17.4

0.89

LV mass (g)

126.6 ± 31.4

132.0 ± 45.1

122.1 ± 22.5

143.2 ± 40.0

0.40

RWT

0.32 ± 0.05

0.32 ± 0.05

0.34 ± 0.05

0.34 ± 0.07

0.82

Left atrial volume (ml)

42.6 ± 11.4

38.8 ± 16.2

34.0 ± 7.5

38.6 ± 10.4

0.34

RV diameter (mm)

30.7 ± 4.2

31.3 ± 5.4

29.3 ± 4.3

31.12 ± 4.3

0.60

PASP (mmHg)

20.5 ± 2.7

21.9 ± 3.6

21.6 ± 3.4

21.2 ± 4.5

0.66

E (cm/s)

80.2 ± 19.3

92.1 ± 14

89.1 ± 14.8

84.1 ± 13.0

0.32

A (cm/s)

52.2 ± 15.5

54.2 ± 11

53.9 ± 8.9

48.2 ± 13.2

0.42

E/A ratio

1.6 ± 0.3

1.8 ± 0.4

1.7 ± 0.4

1.9 ± 0.5

0.47

Deceleration time (ms)

209.8 ± 32.7

201.9 ± 50.3

202.5 ± 35.9

216.9 ± 34.8

0.70

IVRT (ms)

62.2 ± 9.4

67.6 ± 12.8

67.1 ± 10.7

63.1 ± 10.4

0.49

  1. BMI = body mass index. SBP = systolic blood pressure; DBP = diastolic blood pressure; LVEDD = left ventricular end-diastolic diameter; LV = left ventricular; RWT = relative wall thickness; RV = right ventricular; PASP = pulmonary artery systolic pressure; IVRT = isovolumic relaxation time.
  2. *P values for comparison of variables between two groups calculated by Student t test for unpaired data