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Table 2 Clinical variables and mitral inflow after coffee assumption, cigarette smoking, or both. Comparison of clinical and echocardiographic characteristics among groups after coffee assumption, cigarette smoking, or both. Abbreviations are the same used in Tables 1–2.

From: Acute effects of caffeine and cigarette smoking on ventricular long-axis function in healthy subjects

 

Coffee assumption

Cigarette smoking

Coffee assumption and cigarette smoking

Adjusted overall P valueb

Interaction P valuec

 

Change from baseline

P valuea

Change from baseline

P valuea

Change from baseline

P valuea

  

SBP (mmHg)

+1.2%

0.43

+8.6%

0.0010

+4.8%

0.17

-

-

DBP (mmHg)

+3.2%

0.24

+7.6%

0.013

+3.3%

0.30

-

-

HR (bpm)

-3.2%

0.19

+18.7%

< 0.0001

+14.5%

< 0.0001

-

-

SO 2 (%)

-0.2%

0.63

0.3%

0.36

+0.2%

0.58

0.62

0.52

E (cm/s)

-6.1%

0.11

+2.6%

0.80

+0.7%

0.99

0.26

0.15

A (cm/s)

-8.3%

0.06

-2.0%

0.79

+9.3%

0.81

0.29

0.22

E/A ratio

+4.8%

0.19

+10.8%

0.49

-2.7%

0.71

0.68

0.39

DT (ms)

+5.1%

0.99

-1.9%

0.76

-7.8%

0.15

0.34

0.28

IVRT (ms)

+3.8%

0.60

+7.1%

0.41

+5.1%

0.36

0.28

0.92

  1. a Calculated by within-group comparison with baseline value
  2. b P value for the overall effect of testing in the entire population, as determined by two-way ANOVA using a mixed model adjusting for heart rate and blood pressure
  3. c P value for differences in the effect of testing across groups, as determined by two-way ANOVA in a mixed model adjusting for heart rate and blood pressure