Family tree. Family tree showing hypertrophic cardiomyopathy (HCM) phenotypic expression through 3 generations. The three female patients we studied (case-index 1, 63-y; case-index 2, 56-y; case-index 3, 27-y) are represented by black colour filled circles in generations II and III. SCD: Sudden Cardiac death. Squares represent males and circles females. Black colour filled schemes represent HCM patients. Schemes erased by diagonal lines refer to deceased family members.