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Table 2 Baseline and late post-CRT Echocardiographic data.

From: Usefulness of NT-pro BNP monitoring to identify echocardiographic responders following cardiac resynchronization therapy

Variables All patients (n = 42) Responders (n = 29, 69%) Non Responders (n = 13, 31%) P Value
LV geometry and function     
   LV end-systolic Volume, ml     
Baseline 177 ± 65 175 ± 64 189 ± 62 0.49
Late post-CRT 155 ± 67 133 ± 57* 198 ± 67 0.0017
   LV end-diastolic Volume, ml     
Baseline 213 ± 69 209 ± 67 228 ± 67 0.40
Late post-CRT 201 ± 73 181 ± 66* 239 ± 72* 0.01
   LV stroke Volume, ml     
Baseline 42 ± 13 39 ± 10 50 ± 13 0.0048
Late post-CRT 51 ± 11 51 ± 9* 49 ± 14 0.65
   LV ejection fraction, %     
Baseline 19 ± 7 18 ± 7 19 ± 7 0.75
Late post-CRT 24 ± 9 27 ± 9* 18 ± 6 0.0025
   Wall Motion Score Index     
Baseline rest 3.5 ± 0.4 3.4 ± 0.4 3.6 ± 0.2 0.29
Baseline dobutamine 3.1 ± 0.4 3 ± 0.4* 3.3 ± 0.4* 0.038
Contractile Reserve, n (%) 30 (71) 24 (83) 6 (46) 0.02
Mitral Regurgitation     
   Effective orifice Area, mm2     
Baseline 18 ± 13 18 ± 12 17 ± 14 0.73
Late post-CRT 10 ± 11 5 ± 5* 19 ± 15 < 0.0001
   Regurgitant Volume, ml     
Baseline 29 ± 26 31 ± 29 25 ± 19 0.54
Late post-CRT 17 ± 17 11 ± 13* 29 ± 19 0.0009
   Severe Mitral Regurgitation, n (%)     
Baseline 19 (45) 12 (41) 7 (54) 0.45
Late post-CRT 10 (61) 2 (7)* 8 (61) 0.0005
Asynchronism     
   Interventricular, ms 46 ± 27 46 ± 30 45 ± 22 0.92
   Intraventricular, ms 85 ± 25 85 ± 25 85 ± 27 0.93
  1. LV indicates left-ventricular and CRT, cardiac resynchronisation therapy. * significant difference (p < 0.05) between baseline and late post-CRT or between rest and dobutamine data; severe mitral regurgitation is defined as an effective orifice area ≥ 20 mm2.