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Table 1 Comparison of published echocardiographic parameters in rabbits with the three rabbit groups in this report.

From: Hypercholesterolemia and Myocardial function evaluated via Tissue Doppler Imaging

  Literature
(17)
Control
(group 1)
With Ezetemibe
(group 2)
Without Ezetemibe
(group 3)
Weight (kg) 2.59 3.1 ± 0.26 3.11 ± 0.16 3.05 ± 0.2
E/A * 2.19 1.80 ± 0.51 1.92 ± 0.37 1.55 ± 0.49
E'/A'‡ NA 1.93 ± 0.42 1.82 ± 0.22 1.26 ± 0.62
S'‡ NA 6.42 ± 2.55 6.55 ± 1.66 4.6 ± 0.69
E/E' NA 8.91 ± 1.54 8.48 ± 2.15 11.72 ± 5.33
E wave (cm/s) 59 60.6 ± 9.9 59.1 ± 8.5 58.0 ± 9.2
E dec (sec) NA 87.8 ± 22.5 93.4 ± 18.5 102.1 ± 22.1
IVSd (mm) 2.03 2.85 ± 0.37 2.87 ± 0.35 3.11 ± 0.60
IVSs (mm) 3.05 4.14 ± 0.69 4.25 ± 0.70 3.88 ± 0.33
LVIDd (mm) 14.37 15.14 ± 0.69 14.62 ± 2.38 14.77 ± 2.16
LVIDs (mm) 10.05 10.14 ± 0.37 10.5 ± 2.07 10.77 ± 1.85
LVFWd (mm) 2.16 3 ± 0.0 2.5 ± 0.75 2.66 ± 0.5
LVFWs (mm) 3.48 4.14 ± 0.89 3.62 ± 0.51 3.77 ± 0.66
FS (%) 30.13 30.85 ± 3.5 28.37 ± 6.36 28.22 ± 4.76
EF (%) 61.29 62.28 ± 5.02 58.37 ± 9.7 58.44 ± 7.76
Ao (mm) 8.26 9.42 ± 0.78 9.25 ± 1.48 9.33 ± 0.86
LA (mm) 9.66 8.85 ± 1.06 8.5 ± 1.41 9.33 ± 2.64
  1. E wave = Peak E velocity, E dec = E wave decelation time IVSd = Intraventricular septum diastole, IVSs = Intraventricular septum systole, LVIDd = Left ventricular internal dimension diastole, LVIDs = Left ventricular internal dimension systole, LVFWd = Left ventricular free wall diastole, LVFWs = Left ventricular free wall systole, FS = Fractional shortening, EF = Ejection fraction, Ao = Aortic root diameter, LA = Left atrial diameter.
  2. From: Fontes-Sousa, et al. M-mode and Doppler echocardiographic reference values for male New Zealand white rabbits. AJVR 2006;67:1725-1729 (17).
  3. * =p < 0.05 for group 1 vs. group 3
  4. ‡ =p < 0.05 for group 1 and group 2 vs. group 3