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Table 1 Comparison of published echocardiographic parameters in rabbits with the three rabbit groups in this report.

From: Hypercholesterolemia and Myocardial function evaluated via Tissue Doppler Imaging

 

Literature

(17)

Control

(group 1)

With Ezetemibe

(group 2)

Without Ezetemibe

(group 3)

Weight (kg)

2.59

3.1 ± 0.26

3.11 ± 0.16

3.05 ± 0.2

E/A *

2.19

1.80 ± 0.51

1.92 ± 0.37

1.55 ± 0.49

E'/A'‡

NA

1.93 ± 0.42

1.82 ± 0.22

1.26 ± 0.62

S'‡

NA

6.42 ± 2.55

6.55 ± 1.66

4.6 ± 0.69

E/E'

NA

8.91 ± 1.54

8.48 ± 2.15

11.72 ± 5.33

E wave (cm/s)

59

60.6 ± 9.9

59.1 ± 8.5

58.0 ± 9.2

E dec (sec)

NA

87.8 ± 22.5

93.4 ± 18.5

102.1 ± 22.1

IVSd (mm)

2.03

2.85 ± 0.37

2.87 ± 0.35

3.11 ± 0.60

IVSs (mm)

3.05

4.14 ± 0.69

4.25 ± 0.70

3.88 ± 0.33

LVIDd (mm)

14.37

15.14 ± 0.69

14.62 ± 2.38

14.77 ± 2.16

LVIDs (mm)

10.05

10.14 ± 0.37

10.5 ± 2.07

10.77 ± 1.85

LVFWd (mm)

2.16

3 ± 0.0

2.5 ± 0.75

2.66 ± 0.5

LVFWs (mm)

3.48

4.14 ± 0.89

3.62 ± 0.51

3.77 ± 0.66

FS (%)

30.13

30.85 ± 3.5

28.37 ± 6.36

28.22 ± 4.76

EF (%)

61.29

62.28 ± 5.02

58.37 ± 9.7

58.44 ± 7.76

Ao (mm)

8.26

9.42 ± 0.78

9.25 ± 1.48

9.33 ± 0.86

LA (mm)

9.66

8.85 ± 1.06

8.5 ± 1.41

9.33 ± 2.64

  1. E wave = Peak E velocity, E dec = E wave decelation time IVSd = Intraventricular septum diastole, IVSs = Intraventricular septum systole, LVIDd = Left ventricular internal dimension diastole, LVIDs = Left ventricular internal dimension systole, LVFWd = Left ventricular free wall diastole, LVFWs = Left ventricular free wall systole, FS = Fractional shortening, EF = Ejection fraction, Ao = Aortic root diameter, LA = Left atrial diameter.
  2. From: Fontes-Sousa, et al. M-mode and Doppler echocardiographic reference values for male New Zealand white rabbits. AJVR 2006;67:1725-1729 (17).
  3. * =p < 0.05 for group 1 vs. group 3
  4. ‡ =p < 0.05 for group 1 and group 2 vs. group 3